Short-term vasomotor adjustments to post immersion dehydration are hindered by natriuretic peptides

L. Mourot, J. P. Wolf, F. Galland, C. Robinet, A. Courtière, M. Bouhaddi, J. L. Meliet, J. Regnard

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Many studies have described the physiology of water immersion (WI), whereas few have focused on post WI physiology, which faces the global water loss of the large WI diuresis. Therefore, we compared hemodynamics and vasomotor tone in 10 trained supine divers before and after two 6h sessions in dry (DY) and head out WI environments. During each exposure (DY and WI) two exercise periods (each one hour 75W ergometer cycling) started after the 3rd and 5 th hours. Weight losses were significant (-2.24 ± 0.13 kg and -2.38 ± 0.19 kg, after DY and WI, respectively), but not different between the two conditions. Plasma volume was reduced at the end of the two conditions (-9.7 ± 1.6% and -14.7 ± 1.6%, respectively; p<0.05). This post-WI decrease was deeper than post DY (p<0.05). Cardiac output (CO) and mean arterial blood pressure were maintained after the two exposures. Plasma levels of noradrenaline, antidiuretic hormone and ANP were twofold higher after WI than after DY (p<0.05). After DY total peripheral resistances (TPR) were increased (p<0.05) and heart rate (HR) was reduced (p<0.05). After WI there was a trend for a decrease in stroke volume (p=0.07) with unchanged TPR and HR, despite more sizeable increases in plasma noradrenaline and vasopressin than after DY. We hypothesized that the higher levels of plasma natriuretic peptides after WI were likely counteracting the dehydration-required vasomotor adjustments.

Original languageEnglish
Pages (from-to)203-210
Number of pages8
JournalUndersea and Hyperbaric Medicine
Volume31
Issue number2
Publication statusPublished - 1 Jun 2004
Externally publishedYes

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Natriuretic Peptides
Immersion
Dehydration
Water
Vasopressins
Vascular Resistance
Norepinephrine
Arterial Pressure
Heart Rate
Plasma Volume
Diuresis
Atrial Natriuretic Factor
Cardiac Output
Stroke Volume
Weight Loss
Hemodynamics
Head

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Physiology (medical)

Cite this

Mourot, L., Wolf, J. P., Galland, F., Robinet, C., Courtière, A., Bouhaddi, M., ... Regnard, J. (2004). Short-term vasomotor adjustments to post immersion dehydration are hindered by natriuretic peptides. Undersea and Hyperbaric Medicine, 31(2), 203-210.

Short-term vasomotor adjustments to post immersion dehydration are hindered by natriuretic peptides. / Mourot, L.; Wolf, J. P.; Galland, F.; Robinet, C.; Courtière, A.; Bouhaddi, M.; Meliet, J. L.; Regnard, J.

In: Undersea and Hyperbaric Medicine, Vol. 31, No. 2, 01.06.2004, p. 203-210.

Research output: Contribution to journalArticle

Mourot, L, Wolf, JP, Galland, F, Robinet, C, Courtière, A, Bouhaddi, M, Meliet, JL & Regnard, J 2004, 'Short-term vasomotor adjustments to post immersion dehydration are hindered by natriuretic peptides', Undersea and Hyperbaric Medicine, vol. 31, no. 2, pp. 203-210.
Mourot L, Wolf JP, Galland F, Robinet C, Courtière A, Bouhaddi M et al. Short-term vasomotor adjustments to post immersion dehydration are hindered by natriuretic peptides. Undersea and Hyperbaric Medicine. 2004 Jun 1;31(2):203-210.
Mourot, L. ; Wolf, J. P. ; Galland, F. ; Robinet, C. ; Courtière, A. ; Bouhaddi, M. ; Meliet, J. L. ; Regnard, J. / Short-term vasomotor adjustments to post immersion dehydration are hindered by natriuretic peptides. In: Undersea and Hyperbaric Medicine. 2004 ; Vol. 31, No. 2. pp. 203-210.
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