Краткий обзор биомедицинских свойств и применения магниевых сплавов для биоинженерии костной ткани

Translated title of the contribution: Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering

I. A. Khlusov, D. V. Mitrichenko, A. B. Prosolov, O. O. Nikolaeva, G. B. Slepchenko, Yu P. Sharkeev

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Aim: to review current scientific literature concerning the main advances and problems of magnesium (Mg) alloys for traumatology and orthopedics. Methodology of the study. Analytical review based the comprehensive investigation of public scientific and technological sources. Results of the study. Modern knowledge about classification, in vitro and in vivo biodegradation, biomechanics, local and general biocompatibilities, clinical efficacy, and hazards of infectious complications in conditions of osteosynthesis with implants made of Mg alloys with or without protective (anticorrosion and antimicrobial) coatings is presented. Conclusion. Fast degradation and a risk of periprosthetic infection strongly limit clinical application of implants made of Mg and its alloys. Development of novel Mg alloys and their modification by incorporating antimicrobial elements into their body or protective coating is a promising direction to control biomedical characteristics of Mg alloys.

Translated title of the contributionShort review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering
Original languageRussian
Pages (from-to)274-286
Number of pages13
JournalBulletin of Siberian Medicine
Volume18
Issue number2
DOIs
Publication statusPublished - 2019

ASJC Scopus subject areas

  • Molecular Medicine

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