Abstract
A miniaturized analytical system for the separation and amperometric detection of toxic nitrophenols, based on the coupling of a micromachined capillary electrophoresis (CE) chip with a glassy carbon detector is described. This microsystem enables a rapid (120 s/sample) simultaneous determination of five priority nitrophenolic pollutants (2-nitrophenol, 3-nitrophenol, 4-nitrophenol, 2,4-dinitrophenol, and 2-methyl-4,6-dinitrophenol). These compounds can be detected down to the 1 × 10-5 M level using a 15 mM phosphate buffer pH 7.2 (containing 1.3 mM α-cyclodextrin) as running solution on 77 mm long microchannel by applying a separation voltage of 3000 V and a negative potential of -0.7 V (vs. Ag /AgCl wire). Applicability to ground water samples was demonstrated.
| Original language | English |
|---|---|
| Pages (from-to) | 195-199 |
| Number of pages | 5 |
| Journal | Electroanalysis |
| Volume | 18 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Jan 2006 |
| Externally published | Yes |
Fingerprint
Keywords
- Amperometric detection
- Capillary electrophoresis
- Microchip
- Micromachining
- Nitrophenols
ASJC Scopus subject areas
- Analytical Chemistry
- Electrochemistry
Cite this
Separation and detection of nitrophenols at capillary electrophoresis microchips with amperometric detection. / Fischer, Jan; Barek, Jirí; Wang, Joseph.
In: Electroanalysis, Vol. 18, No. 2, 01.01.2006, p. 195-199.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Separation and detection of nitrophenols at capillary electrophoresis microchips with amperometric detection
AU - Fischer, Jan
AU - Barek, Jirí
AU - Wang, Joseph
PY - 2006/1/1
Y1 - 2006/1/1
N2 - A miniaturized analytical system for the separation and amperometric detection of toxic nitrophenols, based on the coupling of a micromachined capillary electrophoresis (CE) chip with a glassy carbon detector is described. This microsystem enables a rapid (120 s/sample) simultaneous determination of five priority nitrophenolic pollutants (2-nitrophenol, 3-nitrophenol, 4-nitrophenol, 2,4-dinitrophenol, and 2-methyl-4,6-dinitrophenol). These compounds can be detected down to the 1 × 10-5 M level using a 15 mM phosphate buffer pH 7.2 (containing 1.3 mM α-cyclodextrin) as running solution on 77 mm long microchannel by applying a separation voltage of 3000 V and a negative potential of -0.7 V (vs. Ag /AgCl wire). Applicability to ground water samples was demonstrated.
AB - A miniaturized analytical system for the separation and amperometric detection of toxic nitrophenols, based on the coupling of a micromachined capillary electrophoresis (CE) chip with a glassy carbon detector is described. This microsystem enables a rapid (120 s/sample) simultaneous determination of five priority nitrophenolic pollutants (2-nitrophenol, 3-nitrophenol, 4-nitrophenol, 2,4-dinitrophenol, and 2-methyl-4,6-dinitrophenol). These compounds can be detected down to the 1 × 10-5 M level using a 15 mM phosphate buffer pH 7.2 (containing 1.3 mM α-cyclodextrin) as running solution on 77 mm long microchannel by applying a separation voltage of 3000 V and a negative potential of -0.7 V (vs. Ag /AgCl wire). Applicability to ground water samples was demonstrated.
KW - Amperometric detection
KW - Capillary electrophoresis
KW - Microchip
KW - Micromachining
KW - Nitrophenols
UR - http://www.scopus.com/inward/record.url?scp=31544466503&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=31544466503&partnerID=8YFLogxK
U2 - 10.1002/elan.200503393
DO - 10.1002/elan.200503393
M3 - Article
VL - 18
SP - 195
EP - 199
JO - Macromolecular Chemistry and Physics
JF - Macromolecular Chemistry and Physics
SN - 1040-0397
IS - 2
ER -