Scintigraphic investigation methods in pulmonary hypertension diagnostics and lesser pulmonary circulation reserve potential evaluation among patients with mitral valve failure

N. G. Krivinogov, V. M. Gulyaev, A. V. Yevtushenko, A. M. Gulyaev, Yu B. Lishmanov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Pulmonary hypertension and bloodstream affection are considered to be major factors that determine indication for operation and limit its successful fulfillment among patients with mitral valve failure. Objective: to develop new systematic approach to radionuclide diagnostics of pulmonary hypertension and to evaluate reserve potential of lesser pulmonary (LP) hemodynamics among patients with mitral valve failure. Materials and methods: 35 patients aged 28 to 55 (the average age rate is 45,0±2,4 years) having II-III stage of mitral stenosis and various pulmonary hypertension intensity have been examined. The evaluation of lesser pulmonary circulation (LPC) potential has been carried out with the application of acute aminophylline test under direct manometry of the right ventricle of heart and pulmonary artery. Obtained data of pressure direct measurement have been compared with the results of radionuclide angiocardiography (RACG). Results: Comparing the results of direct manometry in the right ventricle of heart (RVH) cavities and pulmonary artery (PA) with parameters calculated on the basis of conducted radionuclide investigations, the notions of scintigraphic index "Crvh/Cpa" (correlation of the evacuation constants from the radiophannaceutical right ventricle of heart and pulmonary artery, and mean pulmonary arterial pressure.) During the acute pharmacological aminophyllin test direct connection of pressure in pulmonary artery and right ventricle of heart measured by the direct method with the correlation of CRVH/CPA has been detected. Carried out analysis of the obtained data showed that among people with "positive" reaction for aminophyllin early postoperative period passed without any complications with the parameters recovery of a LP hemodynamics. However, among patients having no LPC reaction for aminophyllin the residual pulmonary hypertension and right ventricular overload after surgical correction was still present. Conclusion: Suggested method of indirect pressure definition in pulmonary artery using radionuclide angiocardiography allows to objectively and accurately evaluate pulmonary hypertension level among patients with mitral valve failure. The application of acute pharmacological aminophyllin test allows to evaluate the reserve potential of lesser pulmonary circulation among such patients.

Original languageEnglish
Title of host publication8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004
Pages346-350
Number of pages5
Volume3
Publication statusPublished - 2005
Event8th Korea-Russia International Symposium on Science and Technology, KORUS 2004 - Tomsk, Russian Federation
Duration: 26 Jun 20043 Jul 2004

Other

Other8th Korea-Russia International Symposium on Science and Technology, KORUS 2004
CountryRussian Federation
CityTomsk
Period26.6.043.7.04

Fingerprint

Radioisotopes
Angiocardiography
Hemodynamics
Recovery

Keywords

  • Aminophyllin
  • Mitral valve failure
  • Pulmonary hypertension
  • Radionuclide angiocardiography

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Krivinogov, N. G., Gulyaev, V. M., Yevtushenko, A. V., Gulyaev, A. M., & Lishmanov, Y. B. (2005). Scintigraphic investigation methods in pulmonary hypertension diagnostics and lesser pulmonary circulation reserve potential evaluation among patients with mitral valve failure. In 8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004 (Vol. 3, pp. 346-350)

Scintigraphic investigation methods in pulmonary hypertension diagnostics and lesser pulmonary circulation reserve potential evaluation among patients with mitral valve failure. / Krivinogov, N. G.; Gulyaev, V. M.; Yevtushenko, A. V.; Gulyaev, A. M.; Lishmanov, Yu B.

8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004. Vol. 3 2005. p. 346-350.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Krivinogov, NG, Gulyaev, VM, Yevtushenko, AV, Gulyaev, AM & Lishmanov, YB 2005, Scintigraphic investigation methods in pulmonary hypertension diagnostics and lesser pulmonary circulation reserve potential evaluation among patients with mitral valve failure. in 8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004. vol. 3, pp. 346-350, 8th Korea-Russia International Symposium on Science and Technology, KORUS 2004, Tomsk, Russian Federation, 26.6.04.
Krivinogov NG, Gulyaev VM, Yevtushenko AV, Gulyaev AM, Lishmanov YB. Scintigraphic investigation methods in pulmonary hypertension diagnostics and lesser pulmonary circulation reserve potential evaluation among patients with mitral valve failure. In 8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004. Vol. 3. 2005. p. 346-350
Krivinogov, N. G. ; Gulyaev, V. M. ; Yevtushenko, A. V. ; Gulyaev, A. M. ; Lishmanov, Yu B. / Scintigraphic investigation methods in pulmonary hypertension diagnostics and lesser pulmonary circulation reserve potential evaluation among patients with mitral valve failure. 8th Korea-Russia International Symposium on Science and Technology - Proceedings: KORUS 2004. Vol. 3 2005. pp. 346-350
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AU - Krivinogov, N. G.

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AU - Yevtushenko, A. V.

AU - Gulyaev, A. M.

AU - Lishmanov, Yu B.

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N2 - Pulmonary hypertension and bloodstream affection are considered to be major factors that determine indication for operation and limit its successful fulfillment among patients with mitral valve failure. Objective: to develop new systematic approach to radionuclide diagnostics of pulmonary hypertension and to evaluate reserve potential of lesser pulmonary (LP) hemodynamics among patients with mitral valve failure. Materials and methods: 35 patients aged 28 to 55 (the average age rate is 45,0±2,4 years) having II-III stage of mitral stenosis and various pulmonary hypertension intensity have been examined. The evaluation of lesser pulmonary circulation (LPC) potential has been carried out with the application of acute aminophylline test under direct manometry of the right ventricle of heart and pulmonary artery. Obtained data of pressure direct measurement have been compared with the results of radionuclide angiocardiography (RACG). Results: Comparing the results of direct manometry in the right ventricle of heart (RVH) cavities and pulmonary artery (PA) with parameters calculated on the basis of conducted radionuclide investigations, the notions of scintigraphic index "Crvh/Cpa" (correlation of the evacuation constants from the radiophannaceutical right ventricle of heart and pulmonary artery, and mean pulmonary arterial pressure.) During the acute pharmacological aminophyllin test direct connection of pressure in pulmonary artery and right ventricle of heart measured by the direct method with the correlation of CRVH/CPA has been detected. Carried out analysis of the obtained data showed that among people with "positive" reaction for aminophyllin early postoperative period passed without any complications with the parameters recovery of a LP hemodynamics. However, among patients having no LPC reaction for aminophyllin the residual pulmonary hypertension and right ventricular overload after surgical correction was still present. Conclusion: Suggested method of indirect pressure definition in pulmonary artery using radionuclide angiocardiography allows to objectively and accurately evaluate pulmonary hypertension level among patients with mitral valve failure. The application of acute pharmacological aminophyllin test allows to evaluate the reserve potential of lesser pulmonary circulation among such patients.

AB - Pulmonary hypertension and bloodstream affection are considered to be major factors that determine indication for operation and limit its successful fulfillment among patients with mitral valve failure. Objective: to develop new systematic approach to radionuclide diagnostics of pulmonary hypertension and to evaluate reserve potential of lesser pulmonary (LP) hemodynamics among patients with mitral valve failure. Materials and methods: 35 patients aged 28 to 55 (the average age rate is 45,0±2,4 years) having II-III stage of mitral stenosis and various pulmonary hypertension intensity have been examined. The evaluation of lesser pulmonary circulation (LPC) potential has been carried out with the application of acute aminophylline test under direct manometry of the right ventricle of heart and pulmonary artery. Obtained data of pressure direct measurement have been compared with the results of radionuclide angiocardiography (RACG). Results: Comparing the results of direct manometry in the right ventricle of heart (RVH) cavities and pulmonary artery (PA) with parameters calculated on the basis of conducted radionuclide investigations, the notions of scintigraphic index "Crvh/Cpa" (correlation of the evacuation constants from the radiophannaceutical right ventricle of heart and pulmonary artery, and mean pulmonary arterial pressure.) During the acute pharmacological aminophyllin test direct connection of pressure in pulmonary artery and right ventricle of heart measured by the direct method with the correlation of CRVH/CPA has been detected. Carried out analysis of the obtained data showed that among people with "positive" reaction for aminophyllin early postoperative period passed without any complications with the parameters recovery of a LP hemodynamics. However, among patients having no LPC reaction for aminophyllin the residual pulmonary hypertension and right ventricular overload after surgical correction was still present. Conclusion: Suggested method of indirect pressure definition in pulmonary artery using radionuclide angiocardiography allows to objectively and accurately evaluate pulmonary hypertension level among patients with mitral valve failure. The application of acute pharmacological aminophyllin test allows to evaluate the reserve potential of lesser pulmonary circulation among such patients.

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KW - Mitral valve failure

KW - Pulmonary hypertension

KW - Radionuclide angiocardiography

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