Abstract
(Chemical Equation Presented) 3,4-Disubstituted and 3,4,5-trisubstituted isoxazoles have been formed from alkynes and nitrile oxides in a ruthenium(II)-catalyzed process (see scheme; cod=cycloocta-l,5-diene, Cp*=C5Me5). These reactions are experimentally simple, proceed at room temperature, and produce isoxazoles with excellent regioselectivity in high yield.
Original language | English |
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Pages (from-to) | 8285-8287 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 47 |
Issue number | 43 |
DOIs | |
Publication status | Published - 13 Oct 2008 |
Externally published | Yes |
Keywords
- Cycloaddition
- Homogeneous catalysis
- Isoxazoles
- Nitrile oxides
- Ruthenium
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis