Ruthenium-catalyzed cycloaddition of aryl azides and alkynes

Lars Kyhn Rasmussen, Brant C. Boren, Valery V. Fokin

Research output: Contribution to journalArticlepeer-review

256 Citations (Scopus)

Abstract

The formation of 1,5-disubstituted 1,2,3-triazoles from aryl azides and alkynes was readily accomplished using [Cp*RuCl]4 catalyst in dimethylformamide. It was also demonstrated that the reaction provided higher yields, cleaner product, and shorter reaction times when carried out under microwave irradiation.

Original languageEnglish
Pages (from-to)5337-5339
Number of pages3
JournalOrganic Letters
Volume9
Issue number26
DOIs
Publication statusPublished - 20 Dec 2007
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

Fingerprint Dive into the research topics of 'Ruthenium-catalyzed cycloaddition of aryl azides and alkynes'. Together they form a unique fingerprint.

Cite this