Abstract
Thirty-nine patients with malignant glioma of the brain were examined at the Center's Clinic. Tumor volume ranged 0.8-175.1 cu cm. Radionuclide diagnosis was obtained with the aid of single-photon emission tomography (E.Cam, Siemens). 99mTc-DTPA, 3-6 MBc/body, was injected intravenously. Smaller size of tumor and lower ratio of differentiated marker accumulation focus/contralateral area were registered in 34%. Simultaneously, a high index of the marker accumulation in the brain was reported, thus suggesting hyperimpermeability of the blood brain barrier. Another 26% revealed larger size of tumor and higher ratio of differentiated 99mTc-DTPA accumulation, likely due to lower impermeability of the blood brain barrier. Hence, use of single-photon emission tomography in diagnosis of malignant cerebral glioma provides a means of evaluating the level of the marker in a tumor node.
| Original language | English |
|---|---|
| Pages (from-to) | 255-259 |
| Number of pages | 5 |
| Journal | Voprosy Onkologii |
| Volume | 57 |
| Issue number | 2 |
| Publication status | Published - 2011 |
Fingerprint
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Role of single-photon emission computer tomography in dynamic evaluation of combined treatment of malignant cerebral glioma. / Sokolov, A. V.; Ivanova, A. A.; Kartashev, A. V.; Vinogradov, V. M.
In: Voprosy Onkologii, Vol. 57, No. 2, 2011, p. 255-259.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role of single-photon emission computer tomography in dynamic evaluation of combined treatment of malignant cerebral glioma
AU - Sokolov, A. V.
AU - Ivanova, A. A.
AU - Kartashev, A. V.
AU - Vinogradov, V. M.
PY - 2011
Y1 - 2011
N2 - Thirty-nine patients with malignant glioma of the brain were examined at the Center's Clinic. Tumor volume ranged 0.8-175.1 cu cm. Radionuclide diagnosis was obtained with the aid of single-photon emission tomography (E.Cam, Siemens). 99mTc-DTPA, 3-6 MBc/body, was injected intravenously. Smaller size of tumor and lower ratio of differentiated marker accumulation focus/contralateral area were registered in 34%. Simultaneously, a high index of the marker accumulation in the brain was reported, thus suggesting hyperimpermeability of the blood brain barrier. Another 26% revealed larger size of tumor and higher ratio of differentiated 99mTc-DTPA accumulation, likely due to lower impermeability of the blood brain barrier. Hence, use of single-photon emission tomography in diagnosis of malignant cerebral glioma provides a means of evaluating the level of the marker in a tumor node.
AB - Thirty-nine patients with malignant glioma of the brain were examined at the Center's Clinic. Tumor volume ranged 0.8-175.1 cu cm. Radionuclide diagnosis was obtained with the aid of single-photon emission tomography (E.Cam, Siemens). 99mTc-DTPA, 3-6 MBc/body, was injected intravenously. Smaller size of tumor and lower ratio of differentiated marker accumulation focus/contralateral area were registered in 34%. Simultaneously, a high index of the marker accumulation in the brain was reported, thus suggesting hyperimpermeability of the blood brain barrier. Another 26% revealed larger size of tumor and higher ratio of differentiated 99mTc-DTPA accumulation, likely due to lower impermeability of the blood brain barrier. Hence, use of single-photon emission tomography in diagnosis of malignant cerebral glioma provides a means of evaluating the level of the marker in a tumor node.
UR - http://www.scopus.com/inward/record.url?scp=79960081313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960081313&partnerID=8YFLogxK
M3 - Article
C2 - 21809676
AN - SCOPUS:79960081313
VL - 57
SP - 255
EP - 259
JO - Voprosy Onkologii
JF - Voprosy Onkologii
SN - 0507-3758
IS - 2
ER -