Abstract
Stroke studies employ experimental models of cerebral ischemic and reperfusion injury in rodents. MRI provides valuable supravital data of cerebral blood flow and brain tissue damage. This paper presents MRI applications for cerebral blood flow research in mice lines with impaired nitric oxide production by endothelial nitric oxide synthase. Our data demonstrates that specific modifications of MRI methodology in transgenic mouse models help to evaluate the role of eNOS in the brain-blood barrier function.
| Original language | English |
|---|---|
| Article number | 012002 |
| Journal | Journal of Physics: Conference Series |
| Volume | 886 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 29 Aug 2017 |
| Event | 3rd International Conference and Young Scientist School on Magnetic Resonance Imaging in Biomedical Research, MRIBiomed 2016 - Novosibirsk, Russian Federation Duration: 23 Nov 2016 → 26 Nov 2016 |
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ASJC Scopus subject areas
- Physics and Astronomy(all)
Cite this
Role of eNOS in water exchange index maintenance-MRI studies. / Atochin, D.; Litvak, M.; Huang, S.; Kim, Y. R.; Huang, P.
In: Journal of Physics: Conference Series, Vol. 886, No. 1, 012002, 29.08.2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role of eNOS in water exchange index maintenance-MRI studies
AU - Atochin, D.
AU - Litvak, M.
AU - Huang, S.
AU - Kim, Y. R.
AU - Huang, P.
PY - 2017/8/29
Y1 - 2017/8/29
N2 - Stroke studies employ experimental models of cerebral ischemic and reperfusion injury in rodents. MRI provides valuable supravital data of cerebral blood flow and brain tissue damage. This paper presents MRI applications for cerebral blood flow research in mice lines with impaired nitric oxide production by endothelial nitric oxide synthase. Our data demonstrates that specific modifications of MRI methodology in transgenic mouse models help to evaluate the role of eNOS in the brain-blood barrier function.
AB - Stroke studies employ experimental models of cerebral ischemic and reperfusion injury in rodents. MRI provides valuable supravital data of cerebral blood flow and brain tissue damage. This paper presents MRI applications for cerebral blood flow research in mice lines with impaired nitric oxide production by endothelial nitric oxide synthase. Our data demonstrates that specific modifications of MRI methodology in transgenic mouse models help to evaluate the role of eNOS in the brain-blood barrier function.
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U2 - 10.1088/1742-6596/886/1/012002
DO - 10.1088/1742-6596/886/1/012002
M3 - Article
AN - SCOPUS:85029594791
VL - 886
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012002
ER -