Relaxivity of Paramagnetic Complexes of Manganese and Gadolinium

O. Yu Borodin, M. Yu Sannikov, M. L. Belyanin, V. D. Filimonov, V. Yu Usov, Yu L. Rybakov, V. M. Gukasov, N. L. Shimanovskii

Research output: Contribution to journalArticle

Abstract

The relaxivities of aqueous solutions of the manganese complexes Mn-CDTA, Mn-DTPA, and Mn-EDTA were compared with that of the gadolinium complex Gd-DTPA. Relaxivities R1 and R2 of Mn-CDTA solutions were slightly greater than those of Gd-DTPA. The lowest relaxivities were seen for Mn-DTPA, while Mn-EDTA occupied an intermediate position between Mc-CTDA and Mn-DTPA.

Original languageEnglish
Pages (from-to)635-637
Number of pages3
JournalPharmaceutical Chemistry Journal
Volume53
Issue number7
DOIs
Publication statusPublished - 1 Oct 2019

Keywords

  • gadolinium complexes
  • magnetic resonance imaging
  • manganese complexes
  • relaxivity

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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