Abstract
Abstract: Reductive amination of cyclohexanone with benzylamine was investigated at 100 °C under 30 bar hydrogen in toluene with five different gold catalysts prepared by deposition–precipitation method and supported on TiO2, La2O3/TiO2, CeO2/TiO2, La2O3 and CeO2. Size of metallic gold varied in the range of 2.6–3.6 nm. The best catalysts in reductive amination of cyclohexanone with benzylamine were 4 wt% Au/TiO2 and 4 wt% Au/CeO2/TiO2 giving 72% and 79% yield of the desired amine. The most acidic and basic catalysts were also unselective and exhibited low activity towards imine hydrogenation. The best catalyst 4 wt% Au/CeO2/TiO2 gave in reductive amination of propiophenone 56% selectivity to the corresponding amine at 20% conversion in 5 h. Graphical Abstract: [Figure not available: see fulltext.]
| Original language | English |
|---|---|
| Journal | Catalysis Letters |
| DOIs | |
| Publication status | Published - 1 Jan 2019 |
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Keywords
- Cyclohexanone
- Gold catalysts
- Propiophenone
- Reductive amination
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
Cite this
Reductive Amination of Ketones with Benzylamine Over Gold Supported on Different Oxides. / Kolobova, E.; Mäki-Arvela, P.; Pestryakov, A.; Pakrieva, E.; Pascual, L.; Smeds, A.; Rahkila, J.; Sandberg, T.; Peltonen, J.; Murzin, D. Yu.
In: Catalysis Letters, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reductive Amination of Ketones with Benzylamine Over Gold Supported on Different Oxides
AU - Kolobova, E.
AU - Mäki-Arvela, P.
AU - Pestryakov, A.
AU - Pakrieva, E.
AU - Pascual, L.
AU - Smeds, A.
AU - Rahkila, J.
AU - Sandberg, T.
AU - Peltonen, J.
AU - Murzin, D. Yu
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Abstract: Reductive amination of cyclohexanone with benzylamine was investigated at 100 °C under 30 bar hydrogen in toluene with five different gold catalysts prepared by deposition–precipitation method and supported on TiO2, La2O3/TiO2, CeO2/TiO2, La2O3 and CeO2. Size of metallic gold varied in the range of 2.6–3.6 nm. The best catalysts in reductive amination of cyclohexanone with benzylamine were 4 wt% Au/TiO2 and 4 wt% Au/CeO2/TiO2 giving 72% and 79% yield of the desired amine. The most acidic and basic catalysts were also unselective and exhibited low activity towards imine hydrogenation. The best catalyst 4 wt% Au/CeO2/TiO2 gave in reductive amination of propiophenone 56% selectivity to the corresponding amine at 20% conversion in 5 h. Graphical Abstract: [Figure not available: see fulltext.]
AB - Abstract: Reductive amination of cyclohexanone with benzylamine was investigated at 100 °C under 30 bar hydrogen in toluene with five different gold catalysts prepared by deposition–precipitation method and supported on TiO2, La2O3/TiO2, CeO2/TiO2, La2O3 and CeO2. Size of metallic gold varied in the range of 2.6–3.6 nm. The best catalysts in reductive amination of cyclohexanone with benzylamine were 4 wt% Au/TiO2 and 4 wt% Au/CeO2/TiO2 giving 72% and 79% yield of the desired amine. The most acidic and basic catalysts were also unselective and exhibited low activity towards imine hydrogenation. The best catalyst 4 wt% Au/CeO2/TiO2 gave in reductive amination of propiophenone 56% selectivity to the corresponding amine at 20% conversion in 5 h. Graphical Abstract: [Figure not available: see fulltext.]
KW - Cyclohexanone
KW - Gold catalysts
KW - Propiophenone
KW - Reductive amination
UR - http://www.scopus.com/inward/record.url?scp=85070086431&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070086431&partnerID=8YFLogxK
U2 - 10.1007/s10562-019-02917-1
DO - 10.1007/s10562-019-02917-1
M3 - Article
JO - Catalysis Letters
JF - Catalysis Letters
SN - 1011-372X
ER -