Reactivity of 2,6-Dichloropurine ribonucleoside studied by 35Cl NQR spectroscopy

I. Dobak, M. Ostafin, O. Kh Poleshchuk, J. Milecki, B. Nogaj

    Research output: Contribution to journalArticle

    Abstract

    2,6-Dichloropurine ribonucleoside is a precursor in the potential synthesis of anticancer and antiviral drugs. 35Cl nuclear quadrupole resonance (NQR) studies on electronic structure and the character of C-Cl bonds may provide a valuable information about the difference in reactivity of chlorine atoms present in this compound. In this work 35Cl NQR frequencies, asymmetry parameters and double-bond character for both C-Cl bonds have been determined experimentally. These parameters were then compared with the corresponding theoretical values obtained by means of the density functional theory.

    Original languageEnglish
    Pages (from-to)47-53
    Number of pages7
    JournalApplied Magnetic Resonance
    Volume34
    Issue number1-2
    DOIs
    Publication statusPublished - Jul 2008

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    ASJC Scopus subject areas

    • Atomic and Molecular Physics, and Optics

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