Abstract
1. The action of sodium amide in ammonia on 4-chloroethynyl-N-alkylpyrazoles having a methyl group at position 5 leads to the formation of rearranged substitution products, i.e., the respective 5-(aminomethyl)-pyrazolylacetylenes. A suggestion is made about the mechanism of the reaction. 2. Under the same conditions 4-bromo- or 4-iodoethynyl-5-methylpyrazoles, like phenylchloroacetylene, exchange the halogen atom for sodium. At the same time a small amount of the aryl- or heteroarylacetonitrile is formed.
| Original language | English |
|---|---|
| Pages (from-to) | 2138-2141 |
| Number of pages | 4 |
| Journal | Bulletin of the Academy of Sciences of the USSR Division of Chemical Science |
| Volume | 25 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1 Oct 1976 |
| Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)
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Cite this
Shavartsberg, M. S., Vasilevskii, S. F., & Sinyakov, A. N. (1976). Reactions of some halocetylenes with sodium amide. Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 25(10), 2138-2141. https://doi.org/10.1007/BF02659534