Reaction of trifluoroacetyl acetylenes with β-amino alcohols. Synthesis of enaminoketones and unusual fragmentation

Maria P. Davydova, Sergey F. Vasilevsky, Valentine G. Nenajdenko

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Graphical abstract Highlights Nucleophilic addition of amino alcohols to CF3CO-acetylenes gave enaminoketones. Diastereoselectivity is determined nature of amino alcohol. New type of fragmentation is observed to form amides and acetophenones. Possible reaction mechanism was proposed.

Original languageEnglish
Pages (from-to)61-67
Number of pages7
JournalJournal of Fluorine Chemistry
Volume190
DOIs
Publication statusPublished - 1 Oct 2016
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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