Reaction of arylpropargyl aldehydes with 2,3-bis-hydroxylamino-2,3-dimethylbutane: Synthesis of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones

Eugene V. Tretyakov, Alexey V. Tkachev, Tatyana V. Rybalova, Yurii V. Gatilov, David W. Knight, Sergey F. Vasilevsky

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Reaction of arylpropargyl aldehydes with 2,3-dihydroxylamino-2,3-dimethylbutane results in the formation of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones in high yields (70-80%). Allowing availability of propargyl aldehydes, this method gives new possibilities for the preparation of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)10075-10080
Number of pages6
JournalTetrahedron
Volume56
Issue number51
DOIs
Publication statusPublished - 15 Dec 2000
Externally publishedYes

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Aldehydes
Availability
2,3-dimethylbutane

Keywords

  • 1-hydroxyimidazolidin-2-ylidenes
  • Hydroxylamine derivatives
  • Propargyl aldehydes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Reaction of arylpropargyl aldehydes with 2,3-bis-hydroxylamino-2,3-dimethylbutane : Synthesis of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones. / Tretyakov, Eugene V.; Tkachev, Alexey V.; Rybalova, Tatyana V.; Gatilov, Yurii V.; Knight, David W.; Vasilevsky, Sergey F.

In: Tetrahedron, Vol. 56, No. 51, 15.12.2000, p. 10075-10080.

Research output: Contribution to journalArticle

Tretyakov, Eugene V. ; Tkachev, Alexey V. ; Rybalova, Tatyana V. ; Gatilov, Yurii V. ; Knight, David W. ; Vasilevsky, Sergey F. / Reaction of arylpropargyl aldehydes with 2,3-bis-hydroxylamino-2,3-dimethylbutane : Synthesis of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones. In: Tetrahedron. 2000 ; Vol. 56, No. 51. pp. 10075-10080.
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abstract = "Reaction of arylpropargyl aldehydes with 2,3-dihydroxylamino-2,3-dimethylbutane results in the formation of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones in high yields (70-80{\%}). Allowing availability of propargyl aldehydes, this method gives new possibilities for the preparation of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones. (C) 2000 Elsevier Science Ltd.",
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T2 - Synthesis of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones

AU - Tretyakov, Eugene V.

AU - Tkachev, Alexey V.

AU - Rybalova, Tatyana V.

AU - Gatilov, Yurii V.

AU - Knight, David W.

AU - Vasilevsky, Sergey F.

PY - 2000/12/15

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AB - Reaction of arylpropargyl aldehydes with 2,3-dihydroxylamino-2,3-dimethylbutane results in the formation of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones in high yields (70-80%). Allowing availability of propargyl aldehydes, this method gives new possibilities for the preparation of 2-(1-hydroxy-4,4,5,5-tetramethylimidazolidin-2-ylidene)-1-arylethanones. (C) 2000 Elsevier Science Ltd.

KW - 1-hydroxyimidazolidin-2-ylidenes

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KW - Propargyl aldehydes

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