Radionuclide assessment of indirect revascularization of the myocardium

Yu B. Lishmanov, Zh V. Vesnina, V. I. Chernov, A. L. Krylov, V. Yu Usov, E. V. Krivoshchekov, Sh D. Akhmedov, T. G. Volkova, V. V. Pekarskij

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Abstract

Fourteen patients with congestive cardiac failure who underwent dynamic cardiomyoplasty (CMP) with m. lattisimus dorsi muscle were examined. Myocardial perfusion was assessed by planar dipyridamole 199Tl scintigraphy and bolus injection of 99mTc into a. thoracodorsalis, followed by measurement of the activity of blood samples collected from the coronary sinus during 30 sec. The mean value of the persistent perfusion defects was unchanged both in the early and late periods after the operation. In 8 patients CMP led to an appreciable decrease of the size of reversible defects due to reduction of left ventricular end diastolic volume. Actual myocardial revascularization resulting from invasion of stimulated myofibrils vasculature into the myocardium may be another cause of reduction of the volume of reversible defects. This phenomenon manifested by increasing radioactivity of coronary sinus blood 10-12 sec after injection of 99mTc in patients after CMP. In controls an increase of blood radioactivity was observed only as a wave of recirculation. Increase of 199Tl heart/lung ratio is an evident sign of hemodynamic improvement.

Original languageEnglish
Pages (from-to)10-13
Number of pages4
JournalMeditsinskaya Radiologiya (Medical Radiology)
Volume40
Issue number2
Publication statusPublished - Mar 1995

ASJC Scopus subject areas

  • Nuclear Energy and Engineering

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    Lishmanov, Y. B., Vesnina, Z. V., Chernov, V. I., Krylov, A. L., Usov, V. Y., Krivoshchekov, E. V., Akhmedov, S. D., Volkova, T. G., & Pekarskij, V. V. (1995). Radionuclide assessment of indirect revascularization of the myocardium. Meditsinskaya Radiologiya (Medical Radiology), 40(2), 10-13.