Radiation-induced reactions in breast cancer patients after breast-conserving surgery with intraoperative and external beam radiotherapy

L. I. Musabaeva, V. A. Lisin, V. V. Velikaia

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    4 Citations (Scopus)

    Abstract

    The present study is aimed to evaluate the frequency and severity of radiation-induced reactions in patients with stage T1-2N0-1M0 breast cancer, who received intraopeartive radiation therapy (IORT) in combination with external beam radiotherapy (EBRT). A small-size betatron producing 6 MeV electron beam was used for IORT. External beam radiotherapy was performed using Rokus and Theratron machines. Radiotherapy treatment was planned using a specially devised method to ensure acceptable levels of severity and frequency of radiation reactions. The patients were divided into 3 groups: the study (40 patients), control (88) and comparison (50) ones. Radiation-induced skin reactions in the study group ranged from erythema to moist desquamation and edema. Magnetic laser therapy was used to treat radiation-induced injuries. The applied method of estimating the total dose of IORT and EBRT was shown to provide the acceptable levels of severity and frequency of radiation reactions.

    Original languageEnglish
    Pages (from-to)474-478
    Number of pages5
    JournalRadiatsionnaya Biologiya. Radioekologiya
    Volume54
    Issue number5
    Publication statusPublished - 1 Sep 2014

    ASJC Scopus subject areas

    • Medicine(all)

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