Protective Effect of Polysaccharides from Tussilago farfara L. on Bone Marrow Cells and Small Intestinal Epithelium Under Conditions of Polychemotherapy Evaluated by DNA Comet Assay

E. A. Safonova, K. A. Lopatina, A. V. Vychuzhanina, V. A. Mashanova, T. G. Razina, T. G. Borovskaya, E. P. Zueva, A. M. Gur’ev, M. V. Belousov

Research output: Contribution to journalArticle

Abstract

Using DNA comet assay we found that polysaccharides from Tussilago farfara L. reduced the intensity of polychemotherapy-induced apoptosis and DNA damage in bone marrow cells and small intestinal epithelium of C57Bl/6 mice, which attested to genoprotective properties of these polysaccharides.

Original languageEnglish
JournalBulletin of Experimental Biology and Medicine
DOIs
Publication statusAccepted/In press - 1 Jan 2018

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Keywords

  • bone marrow
  • DNA
  • polychemotherapy
  • polysaccharides
  • small intestine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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