Properties of the "orgamax" osteoplastic material made of a demineralized allograft bone

Abstract

We investigated properties of the "Orgamax" osteoplastic material, which was produced from a demineralized bone, in the treatment of extensive caries, in particular chronic pulpitis of the permanent teeth with unformed roots in children. The "Orgamax" osteoplastic material consists of demineralized bone chips, a collagen additive, and antibiotics. The surface morphology of the "Orgamax" osteoplastic material is macroporous, with the maximum pore size of 250 μm, whereas the surface morphology of the major component of "Orgamax", demineralized bone chips, is microporous, with a pore size of 10-20 μm. Material "Orgamax" is used in the treatment of complicated caries, particularly chronic pulpitis of permanent teeth with unformed roots in children. "Orgamax" filling a formed cavity exhibits antimicrobial properties, eliminates inflammation in the dental pulp, and, due to its osteoconductive and osteoinductive properties, undergoes gradual resorption, stimulates regeneration, and provides replacement of the defect with newly formed tissue. The dental pulp viability is completely restored, which ensures the complete formation of tooth roots with root apex closure in the long-term period.

Original language	English
Article number	020053
Journal	AIP Conference Proceedings
Volume	1760
DOIs	https://doi.org/10.1063/1.4960272
Publication status	Published - 2 Aug 2016
Event	International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016, PC 2016 - Tomsk, Russian Federation Duration: 22 Mar 2016 → 25 Mar 2016

ASJC Scopus subject areas

Physics and Astronomy(all)

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10.1063/1.4960272

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Podorognaya, V. T., Kirilova, I. A., Sharkeev, Y. P., Uvarkin, P. V., Zhelezny, P. A., Zheleznaya, A. P., Akimova, S. E., Novoselov, V. P., & Tupikova, L. N. (2016). Properties of the "orgamax" osteoplastic material made of a demineralized allograft bone. AIP Conference Proceedings, 1760, [020053]. https://doi.org/10.1063/1.4960272

Properties of the "orgamax" osteoplastic material made of a demineralized allograft bone. / Podorognaya, V. T.; Kirilova, I. A.; Sharkeev, Yury Petrovich; Uvarkin, P. V.; Zhelezny, P. A.; Zheleznaya, A. P.; Akimova, S. E.; Novoselov, V. P.; Tupikova, L. N.

In: AIP Conference Proceedings, Vol. 1760, 020053, 02.08.2016.

Research output: Contribution to journal › Article

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abstract = "We investigated properties of the {"}Orgamax{"} osteoplastic material, which was produced from a demineralized bone, in the treatment of extensive caries, in particular chronic pulpitis of the permanent teeth with unformed roots in children. The {"}Orgamax{"} osteoplastic material consists of demineralized bone chips, a collagen additive, and antibiotics. The surface morphology of the {"}Orgamax{"} osteoplastic material is macroporous, with the maximum pore size of 250 μm, whereas the surface morphology of the major component of {"}Orgamax{"}, demineralized bone chips, is microporous, with a pore size of 10-20 μm. Material {"}Orgamax{"} is used in the treatment of complicated caries, particularly chronic pulpitis of permanent teeth with unformed roots in children. {"}Orgamax{"} filling a formed cavity exhibits antimicrobial properties, eliminates inflammation in the dental pulp, and, due to its osteoconductive and osteoinductive properties, undergoes gradual resorption, stimulates regeneration, and provides replacement of the defect with newly formed tissue. The dental pulp viability is completely restored, which ensures the complete formation of tooth roots with root apex closure in the long-term period.",

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