Prognosis of dynamics of myocardial perfusion in patients with essential hypertension on calcium antagonists

E. N. Pavlyukova, V. P. Leonov, N. S. Binderis, V. I. Chernov, R. S. Karpov

Research output: Contribution to journalArticlepeer-review

Abstract

The state of myocardial perfusion was studied in patients with stage II hypertensive disease (essential hypertension) during long-term monotherapy with calcium antagonists. Possibilities to predict dynamics of myocardial perfusion were evaluated. Three types of reaction of myocardial perfusion to dipyridamole tests conducted during monotherapy with calcium antagonists were distinguished: increase of hypoperfusion, decrease of hypoperfusion, and no change. There were no significant differences between effects of verapamil, diltiazem and nifedipine on myocardial perfusion. Dynamics of myocardial perfusion could be predicted by the set of echocardiographic indices obtained before treatment (among them isometric relaxation, relations of peak transmitral flows during dipyridamole test and left ventricular myocardial mass).

Original languageEnglish
Pages (from-to)22-26
Number of pages5
JournalKardiologiya
Volume36
Issue number9
Publication statusPublished - 1996

Keywords

  • Calcium antagonists
  • Hypertension, essential
  • Myocardial perfusion, dynamics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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