Production of novel ceramic porous surfaces tailored for bone tissue engineering

Nikolaos Michailidis, Fani Stergioudi, Konstantina Viglaki, Maria Chatzinikolaidou

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Moderate toughness and poor biological features of ceramics may hinder their application as modern bio-active implants. The paper presents a new, cost-effective, environmentally friendly and simple production method of open-cell calcium phosphate (CP) ceramic foams, by employing powders' compaction, dissolution and sintering, aiming at producing highly bio-active 3D surface scaffolds. The process parameters were properly adjusted to optimize the quality and structure of CP foams, and samples with various porosity (60-75 vol%) and pore size (0.28-0.50 mm) were fabricated, characterized and mechanically tested. Cell viability, adhesion and proliferation investigations revealed an excellent potential for application in bone tissue engineering.

Original languageEnglish
Pages (from-to)557-560
Number of pages4
JournalCIRP Annals - Manufacturing Technology
Volume63
Issue number1
DOIs
Publication statusPublished - 2014
Externally publishedYes

Keywords

  • Biomedical surfaces
  • Cell growth
  • Powder sintering

ASJC Scopus subject areas

  • Mechanical Engineering
  • Industrial and Manufacturing Engineering

Fingerprint Dive into the research topics of 'Production of novel ceramic porous surfaces tailored for bone tissue engineering'. Together they form a unique fingerprint.

Cite this