Abstract
Agonists of δ1- and δ2-opiate receptors prevent epinephrine-induced arrhythmias in rats after intracerebroventricular administration. The antagonist of δ-opiate receptors ICI 174,864 blocks antiarrhythmic effect of the selective agonist of δ-opiate receptors DTLET and exhibits no antiarrhythmic activity by itself. It is shown that antiarrhythmic effect of DTLET is associated with increased vagal tone.
Original language | English |
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Pages (from-to) | 873-875 |
Number of pages | 3 |
Journal | Bulletin of Experimental Biology and Medicine |
Volume | 124 |
Issue number | 9 |
Publication status | Published - Sep 1997 |
Keywords
- δ- and δ-opiate receptors
- Arrhythmia
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)