Agonists of δ1- and δ2-opiate receptors prevent epinephrine-induced arrhythmias in rats after intracerebroventricular administration. The antagonist of δ-opiate receptors ICI 174,864 blocks antiarrhythmic effect of the selective agonist of δ-opiate receptors DTLET and exhibits no antiarrhythmic activity by itself. It is shown that antiarrhythmic effect of DTLET is associated with increased vagal tone.
|Number of pages||3|
|Journal||Bulletin of Experimental Biology and Medicine|
|Publication status||Published - Sep 1997|
- δ- and δ-opiate receptors
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)