Preparation of Poly(L-lactic acid)/Hydroxyapatite composite scaffolds by fused deposit modeling 3D printing

Abstract

In this work, method of preparation FDM 3D printed PLLA/HAp composite scaffolds of three compositions (12.5, 25, and 50 wt.% of HAp) was proposed. Influence of hydroxyapatite weight fraction on morphological and mechanical properties of PLLA/HAp composite scaffolds was studied. Morphological and mechanical properties of 3D-pinted scaffolds were investigated by scanning electron microscopy and nanoindentation. Results of scanning electron microscopy analysis showed that proposed method of composite mixing allows obtaining highly filled composites with homogeneous distribution of HAp powder in the PLLA-matrix. Results of nanoindentation showed growth of Young's modulus with an increasing of HAp weight fraction. The maximum value of 8111 ± 714 MPa Young's modulus was reached for the composite with 50 wt.% of HAp.

Original language	English
Pages (from-to)	228-234
Number of pages	7
Journal	Materials Today: Proceedings
Volume	22
DOIs	https://doi.org/10.1016/j.matpr.2019.08.092
Publication status	Published - 1 Jan 2020
Event	2018 2nd International Conference on Nanomaterials and Biomaterials, ICNB 2018 - Barcelona, Spain Duration: 10 Dec 2018 → 12 Dec 2018

Keywords

3d printing
Composite
Hydroxyapatite
Poly(L-lactic acid)

ASJC Scopus subject areas

Materials Science(all)

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10.1016/j.matpr.2019.08.092

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@article{b819306d69314d93b8f1c2aaeb9bbedb,

title = "Preparation of Poly(L-lactic acid)/Hydroxyapatite composite scaffolds by fused deposit modeling 3D printing",

abstract = "In this work, method of preparation FDM 3D printed PLLA/HAp composite scaffolds of three compositions (12.5, 25, and 50 wt.% of HAp) was proposed. Influence of hydroxyapatite weight fraction on morphological and mechanical properties of PLLA/HAp composite scaffolds was studied. Morphological and mechanical properties of 3D-pinted scaffolds were investigated by scanning electron microscopy and nanoindentation. Results of scanning electron microscopy analysis showed that proposed method of composite mixing allows obtaining highly filled composites with homogeneous distribution of HAp powder in the PLLA-matrix. Results of nanoindentation showed growth of Young's modulus with an increasing of HAp weight fraction. The maximum value of 8111 ± 714 MPa Young's modulus was reached for the composite with 50 wt.% of HAp.",

keywords = "3d printing, Composite, Hydroxyapatite, Poly(L-lactic acid)",

author = "Dubinenko, {Gleb E.} and Zinoviev, {Alexey L.} and Bolbasov, {Evgeniy N.} and Novikov, {Viktor T.} and Tverdokhlebov, {Sergey I.}",

year = "2020",

month = jan,

day = "1",

doi = "10.1016/j.matpr.2019.08.092",

language = "English",

volume = "22",

pages = "228--234",

journal = "Materials Today: Proceedings",

issn = "2214-7853",

publisher = "Elsevier Limited",

note = "2018 2nd International Conference on Nanomaterials and Biomaterials, ICNB 2018 ; Conference date: 10-12-2018 Through 12-12-2018",

}

TY - JOUR

T1 - Preparation of Poly(L-lactic acid)/Hydroxyapatite composite scaffolds by fused deposit modeling 3D printing

AU - Dubinenko, Gleb E.

AU - Zinoviev, Alexey L.

AU - Bolbasov, Evgeniy N.

AU - Novikov, Viktor T.

AU - Tverdokhlebov, Sergey I.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - In this work, method of preparation FDM 3D printed PLLA/HAp composite scaffolds of three compositions (12.5, 25, and 50 wt.% of HAp) was proposed. Influence of hydroxyapatite weight fraction on morphological and mechanical properties of PLLA/HAp composite scaffolds was studied. Morphological and mechanical properties of 3D-pinted scaffolds were investigated by scanning electron microscopy and nanoindentation. Results of scanning electron microscopy analysis showed that proposed method of composite mixing allows obtaining highly filled composites with homogeneous distribution of HAp powder in the PLLA-matrix. Results of nanoindentation showed growth of Young's modulus with an increasing of HAp weight fraction. The maximum value of 8111 ± 714 MPa Young's modulus was reached for the composite with 50 wt.% of HAp.

AB - In this work, method of preparation FDM 3D printed PLLA/HAp composite scaffolds of three compositions (12.5, 25, and 50 wt.% of HAp) was proposed. Influence of hydroxyapatite weight fraction on morphological and mechanical properties of PLLA/HAp composite scaffolds was studied. Morphological and mechanical properties of 3D-pinted scaffolds were investigated by scanning electron microscopy and nanoindentation. Results of scanning electron microscopy analysis showed that proposed method of composite mixing allows obtaining highly filled composites with homogeneous distribution of HAp powder in the PLLA-matrix. Results of nanoindentation showed growth of Young's modulus with an increasing of HAp weight fraction. The maximum value of 8111 ± 714 MPa Young's modulus was reached for the composite with 50 wt.% of HAp.

KW - 3d printing

KW - Composite

KW - Hydroxyapatite

KW - Poly(L-lactic acid)

UR - http://www.scopus.com/inward/record.url?scp=85081978866&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85081978866&partnerID=8YFLogxK

U2 - 10.1016/j.matpr.2019.08.092

DO - 10.1016/j.matpr.2019.08.092

M3 - Conference article

AN - SCOPUS:85081978866

VL - 22

SP - 228

EP - 234

JO - Materials Today: Proceedings

JF - Materials Today: Proceedings

SN - 2214-7853

T2 - 2018 2nd International Conference on Nanomaterials and Biomaterials, ICNB 2018

Y2 - 10 December 2018 through 12 December 2018