Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study: Structure and osteoblast-like MG63 cells in vitro study

M. A. Surmeneva, A. Kovtun, A. Peetsch, S. N. Goroja, A. A. Sharonova, V. F. Pichugin, I. Y. Grubova, A. A. Ivanova, A. D. Teresov, Nikolay Nikolaevich Koval, V. Buck, A. Wittmar, M. Ulbricht, O. Prymak, M. Epple, R. A. Surmenev

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.

Original languageEnglish
Pages (from-to)11240-11246
Number of pages7
JournalRSC Advances
Volume3
Issue number28
DOIs
Publication statusPublished - 28 Jul 2013

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)

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