Abstract
Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.
| Original language | English |
|---|---|
| Pages (from-to) | 11240-11246 |
| Number of pages | 7 |
| Journal | RSC Advances |
| Volume | 3 |
| Issue number | 28 |
| DOIs | |
| Publication status | Published - 28 Jul 2013 |
Fingerprint
ASJC Scopus subject areas
- Chemical Engineering(all)
- Chemistry(all)
Cite this
Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study : Structure and osteoblast-like MG63 cells in vitro study. / Surmeneva, M. A.; Kovtun, A.; Peetsch, A.; Goroja, S. N.; Sharonova, A. A.; Pichugin, V. F.; Grubova, I. Y.; Ivanova, A. A.; Teresov, A. D.; Koval, Nikolay Nikolaevich; Buck, V.; Wittmar, A.; Ulbricht, M.; Prymak, O.; Epple, M.; Surmenev, R. A.
In: RSC Advances, Vol. 3, No. 28, 28.07.2013, p. 11240-11246.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study
T2 - Structure and osteoblast-like MG63 cells in vitro study
AU - Surmeneva, M. A.
AU - Kovtun, A.
AU - Peetsch, A.
AU - Goroja, S. N.
AU - Sharonova, A. A.
AU - Pichugin, V. F.
AU - Grubova, I. Y.
AU - Ivanova, A. A.
AU - Teresov, A. D.
AU - Koval, Nikolay Nikolaevich
AU - Buck, V.
AU - Wittmar, A.
AU - Ulbricht, M.
AU - Prymak, O.
AU - Epple, M.
AU - Surmenev, R. A.
PY - 2013/7/28
Y1 - 2013/7/28
N2 - Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.
AB - Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.
UR - http://www.scopus.com/inward/record.url?scp=84879509077&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84879509077&partnerID=8YFLogxK
U2 - 10.1039/c3ra40446c
DO - 10.1039/c3ra40446c
M3 - Article
VL - 3
SP - 11240
EP - 11246
JO - RSC Advances
JF - RSC Advances
SN - 2046-2069
IS - 28
ER -