Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study: Structure and osteoblast-like MG63 cells in vitro study

Abstract

Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.

Original language	English
Pages (from-to)	11240-11246
Number of pages	7
Journal	RSC Advances
Volume	3
Issue number	28
DOIs	https://doi.org/10.1039/c3ra40446c https://doi.org/10.1039/c3ra40446c
Publication status	Published - 28 Jul 2013

ASJC Scopus subject areas

Chemical Engineering(all)
Chemistry(all)

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Surmeneva, M. A., Kovtun, A., Peetsch, A., Goroja, S. N., Sharonova, A. A., Pichugin, V. F., Grubova, I. Y., Ivanova, A. A., Teresov, A. D., Koval, N. N., Buck, V., Wittmar, A., Ulbricht, M., Prymak, O., Epple, M., & Surmenev, R. A. (2013). Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study: Structure and osteoblast-like MG63 cells in vitro study. RSC Advances, 3(28), 11240-11246. https://doi.org/10.1039/c3ra40446c, https://doi.org/10.1039/c3ra40446c

Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study : Structure and osteoblast-like MG63 cells in vitro study. / Surmeneva, M. A.; Kovtun, A.; Peetsch, A.; Goroja, S. N.; Sharonova, A. A.; Pichugin, V. F.; Grubova, I. Y.; Ivanova, A. A.; Teresov, A. D.; Koval, Nikolay Nikolaevich; Buck, V.; Wittmar, A.; Ulbricht, M.; Prymak, O.; Epple, M.; Surmenev, R. A.

In: RSC Advances, Vol. 3, No. 28, 28.07.2013, p. 11240-11246.

Research output: Contribution to journal › Article

Surmeneva, MA, Kovtun, A, Peetsch, A, Goroja, SN , Sharonova, AA , Pichugin, VF , Grubova, IY , Ivanova, AA, Teresov, AD, Koval, NN, Buck, V, Wittmar, A, Ulbricht, M, Prymak, O, Epple, M & Surmenev, RA 2013, 'Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study: Structure and osteoblast-like MG63 cells in vitro study', RSC Advances, vol. 3, no. 28, pp. 11240-11246. https://doi.org/10.1039/c3ra40446c, https://doi.org/10.1039/c3ra40446c

Surmeneva MA, Kovtun A, Peetsch A, Goroja SN , Sharonova AA , Pichugin VF et al. Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study: Structure and osteoblast-like MG63 cells in vitro study. RSC Advances. 2013 Jul 28;3(28):11240-11246. https://doi.org/10.1039/c3ra40446c, https://doi.org/10.1039/c3ra40446c

Surmeneva, M. A. ; Kovtun, A. ; Peetsch, A. ; Goroja, S. N. ; Sharonova, A. A. ; Pichugin, V. F. ; Grubova, I. Y. ; Ivanova, A. A. ; Teresov, A. D. ; Koval, Nikolay Nikolaevich ; Buck, V. ; Wittmar, A. ; Ulbricht, M. ; Prymak, O. ; Epple, M. ; Surmenev, R. A. / Preparation of a silicate-containing hydroxyapatite-based coating by magnetron sputtering: structure and osteoblast-like MG63 cells in vitro study : Structure and osteoblast-like MG63 cells in vitro study. In: RSC Advances. 2013 ; Vol. 3, No. 28. pp. 11240-11246.

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abstract = "Silicate-containing hydroxyapatite-based coatings with different structure and calcium/phosphate ratios were prepared by radio-frequency magnetron sputtering on silicon and titanium substrates, respectively. Scanning electron microscopy, X-ray diffraction and IR spectroscopy were used to investigate the effect of the substrate bias on the properties of the silicate-containing hydroxyapatite-based coatings. The deposition rate, composition, and microstructure of the deposited coatings were all controlled by changing the bias voltage from grounded (0 V) to -50 and -100 V. The biocompatibility was assessed by cell culture with human osteoblast-like cells (MG-63 cell line), showing a good biocompatibility and cell growth on the substrates.",

author = "Surmeneva, {M. A.} and A. Kovtun and A. Peetsch and Goroja, {S. N.} and Sharonova, {A. A.} and Pichugin, {V. F.} and Grubova, {I. Y.} and Ivanova, {A. A.} and Teresov, {A. D.} and Koval, {Nikolay Nikolaevich} and V. Buck and A. Wittmar and M. Ulbricht and O. Prymak and M. Epple and Surmenev, {R. A.}",

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T2 - Structure and osteoblast-like MG63 cells in vitro study

AU - Surmeneva, M. A.

AU - Kovtun, A.

AU - Peetsch, A.

AU - Goroja, S. N.

AU - Sharonova, A. A.

AU - Pichugin, V. F.

AU - Grubova, I. Y.

AU - Ivanova, A. A.

AU - Teresov, A. D.

AU - Koval, Nikolay Nikolaevich

AU - Buck, V.

AU - Wittmar, A.

AU - Ulbricht, M.

AU - Prymak, O.

AU - Epple, M.

AU - Surmenev, R. A.

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Y1 - 2013/7/28

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