Abstract
Various 1-arylbenziodoxolones can be conveniently prepared from 2-iodobenzoic acid and arenes by a one-pot procedure using Oxone (2KHSO 5·KHSO4·K2SO4) as an inexpensive and environmentally safe oxidant. This procedure is also applicable for the synthesis of the 7-methylbenziodoxolone ring system using 2-iodo-3-methylbenzoic acid as starting compound. Structures of four 1-arylbenziodoxolone derivatives were established by single-crystal X-ray diffraction analysis. An enhanced reactivity of 1-aryl-7-methylbenziodoxolones toward nucleophiles compared to unsubstituted 1-arylbenziodoxolones has been found.
Original language | English |
---|---|
Pages (from-to) | 3767-3773 |
Number of pages | 7 |
Journal | Journal of Organic Chemistry |
Volume | 78 |
Issue number | 8 |
DOIs | |
Publication status | Published - 19 Apr 2013 |
ASJC Scopus subject areas
- Organic Chemistry