Preparation and X-ray structural study of 1-arylbenziodoxolones

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Various 1-arylbenziodoxolones can be conveniently prepared from 2-iodobenzoic acid and arenes by a one-pot procedure using Oxone (2KHSO 5·KHSO4·K2SO4) as an inexpensive and environmentally safe oxidant. This procedure is also applicable for the synthesis of the 7-methylbenziodoxolone ring system using 2-iodo-3-methylbenzoic acid as starting compound. Structures of four 1-arylbenziodoxolone derivatives were established by single-crystal X-ray diffraction analysis. An enhanced reactivity of 1-aryl-7-methylbenziodoxolones toward nucleophiles compared to unsubstituted 1-arylbenziodoxolones has been found.

Original languageEnglish
Pages (from-to)3767-3773
Number of pages7
JournalJournal of Organic Chemistry
Volume78
Issue number8
DOIs
Publication statusPublished - 19 Apr 2013

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X rays
Nucleophiles
Oxidants
X ray diffraction analysis
Single crystals
Derivatives
7-methylbenziodoxolone
3-toluic acid
2-iodobenzoic acid
potassium peroxymonosulfuric acid

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Preparation and X-ray structural study of 1-arylbenziodoxolones. / Yusubov, Mekhman S.; Yusubova, Roza Y.; Nemykin, Victor N.; Zhdankin, Viktor Vladimirovich.

In: Journal of Organic Chemistry, Vol. 78, No. 8, 19.04.2013, p. 3767-3773.

Research output: Contribution to journalArticle

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