Abstract
(Chemical Equation Presented) A direct, simple, and efficient route from terminal alkynes to amides is achieved by their copper(I)-catalyzed reaction with sulfonyl azides (see scheme). The reaction proceeds with the in situ generation of copper(I) acetylides and represents a one-step formal oxidative hydration of a triple bond.
Original language | English |
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Pages (from-to) | 3154-3157 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 45 |
Issue number | 19 |
DOIs | |
Publication status | Published - 5 May 2006 |
Externally published | Yes |
Keywords
- Alkynes
- Azides
- Copper
- Oxidation
- Synthetic methods
ASJC Scopus subject areas
- Chemistry(all)