Possibilities of <sup>18</sup>F-FDG PET/CT in the diagnosis and staging of lymphomas

Abstract

The aim of the study was to evaluate the effectiveness of 18F-FDG PET/CT in lymphomas staging compared with traditional diagnostic methods. The results of ¹⁸F-FDG PET/ CT of 30 patients with malignant lymphomas were analyzed. The j analysis showed high efficiency of 18F-FDG PET/CT compared with standard clinical and instrumental methods of research. This method has demonstrated the greatest diagnostic value in the diagnosis of involvement of the iliac, mediastinal, mesenteric and inguinal lymph nodes in the tumor process, as well^as in extronadal lesions (red bone marrow, son tissues, lungs and spleen), when sensitivity was 90% or more. The mismatch between the results of traditional research methods and 18F-FDG PET/CT in lymphoma staging was found in 12 (40%) patients: in 4 cases 18F-FDG PET/CT allowed to lower the stage of the disease, and in 8 patients to increase, which allowed correcting the therapy in 23% of patients. Thus, the results of the study indicate a high efficacy of 18F-FDG PET/ CT for malignant lymphomas staging.

Original language	English
Pages (from-to)	147-153
Number of pages	7
Journal	Voprosy Onkologii
Volume	65
Issue number	1
Publication status	Published - 2019

ASJC Scopus subject areas

Oncology
Cancer Research

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Possibilities of ¹⁸F-FDG PET/CT in the diagnosis and staging of lymphomas. / Chanchikova, N. G.; Dudnikova, E. A.; Karlova, E. A.; Savefyev, A. S.; Silkina, O. A.; Zelchan, R. V.; Sinilkin, L. G.; Bragina, O. D.; Medvedeva, A. A.; Chernov, V. I.

In: Voprosy Onkologii, Vol. 65, No. 1, 2019, p. 147-153.

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title = "Possibilities of 18F-FDG PET/CT in the diagnosis and staging of lymphomas",

abstract = "The aim of the study was to evaluate the effectiveness of 18F-FDG PET/CT in lymphomas staging compared with traditional diagnostic methods. The results of 18F-FDG PET/ CT of 30 patients with malignant lymphomas were analyzed. The j analysis showed high efficiency of 18F-FDG PET/CT compared with standard clinical and instrumental methods of research. This method has demonstrated the greatest diagnostic value in the diagnosis of involvement of the iliac, mediastinal, mesenteric and inguinal lymph nodes in the tumor process, as well^as in extronadal lesions (red bone marrow, son tissues, lungs and spleen), when sensitivity was 90% or more. The mismatch between the results of traditional research methods and 18F-FDG PET/CT in lymphoma staging was found in 12 (40%) patients: in 4 cases 18F-FDG PET/CT allowed to lower the stage of the disease, and in 8 patients to increase, which allowed correcting the therapy in 23% of patients. Thus, the results of the study indicate a high efficacy of 18F-FDG PET/ CT for malignant lymphomas staging.",

author = "Chanchikova, {N. G.} and Dudnikova, {E. A.} and Karlova, {E. A.} and Savefyev, {A. S.} and Silkina, {O. A.} and Zelchan, {R. V.} and Sinilkin, {L. G.} and Bragina, {O. D.} and Medvedeva, {A. A.} and Chernov, {V. I.}",

year = "2019",

language = "English",

volume = "65",

pages = "147--153",

journal = "Voprosy Onkologii",

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AU - Chanchikova, N. G.

AU - Dudnikova, E. A.

AU - Karlova, E. A.

AU - Savefyev, A. S.

AU - Silkina, O. A.

AU - Zelchan, R. V.

AU - Sinilkin, L. G.

AU - Bragina, O. D.

AU - Medvedeva, A. A.

AU - Chernov, V. I.

PY - 2019

Y1 - 2019

N2 - The aim of the study was to evaluate the effectiveness of 18F-FDG PET/CT in lymphomas staging compared with traditional diagnostic methods. The results of 18F-FDG PET/ CT of 30 patients with malignant lymphomas were analyzed. The j analysis showed high efficiency of 18F-FDG PET/CT compared with standard clinical and instrumental methods of research. This method has demonstrated the greatest diagnostic value in the diagnosis of involvement of the iliac, mediastinal, mesenteric and inguinal lymph nodes in the tumor process, as well^as in extronadal lesions (red bone marrow, son tissues, lungs and spleen), when sensitivity was 90% or more. The mismatch between the results of traditional research methods and 18F-FDG PET/CT in lymphoma staging was found in 12 (40%) patients: in 4 cases 18F-FDG PET/CT allowed to lower the stage of the disease, and in 8 patients to increase, which allowed correcting the therapy in 23% of patients. Thus, the results of the study indicate a high efficacy of 18F-FDG PET/ CT for malignant lymphomas staging.

AB - The aim of the study was to evaluate the effectiveness of 18F-FDG PET/CT in lymphomas staging compared with traditional diagnostic methods. The results of 18F-FDG PET/ CT of 30 patients with malignant lymphomas were analyzed. The j analysis showed high efficiency of 18F-FDG PET/CT compared with standard clinical and instrumental methods of research. This method has demonstrated the greatest diagnostic value in the diagnosis of involvement of the iliac, mediastinal, mesenteric and inguinal lymph nodes in the tumor process, as well^as in extronadal lesions (red bone marrow, son tissues, lungs and spleen), when sensitivity was 90% or more. The mismatch between the results of traditional research methods and 18F-FDG PET/CT in lymphoma staging was found in 12 (40%) patients: in 4 cases 18F-FDG PET/CT allowed to lower the stage of the disease, and in 8 patients to increase, which allowed correcting the therapy in 23% of patients. Thus, the results of the study indicate a high efficacy of 18F-FDG PET/ CT for malignant lymphomas staging.

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