Polytriazoles as copper(I)-stabilizing ligands in catalysis

Timothy R. Chan, Robert Hilgraf, K. Barry Sharpless, Valery V. Fokin

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Abstract

(Equation Presented) Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.

Original languageEnglish
Pages (from-to)2853-2855
Number of pages3
JournalOrganic Letters
Volume6
Issue number17
DOIs
Publication statusPublished - 19 Aug 2004
Externally publishedYes

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ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Chan, T. R., Hilgraf, R., Sharpless, K. B., & Fokin, V. V. (2004). Polytriazoles as copper(I)-stabilizing ligands in catalysis. Organic Letters, 6(17), 2853-2855. https://doi.org/10.1021/ol0493094