Polytriazoles as copper(I)-stabilizing ligands in catalysis

Timothy R. Chan, Robert Hilgraf, K. Barry Sharpless, Valery V. Fokin

Research output: Contribution to journal › Article

Abstract

(Equation Presented) Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C₃-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.

Original language	English
Pages (from-to)	2853-2855
Number of pages	3
Journal	Organic Letters
Volume	6
Issue number	17
DOIs	https://doi.org/10.1021/ol0493094
Publication status	Published - 19 Aug 2004
Externally published	Yes

Fingerprint

Catalysis

catalysis

Copper

Ligands

copper

ligands

Alkynes

Azides

alkynes

Ligation

catalytic activity

Catalyst activity

Derivatives

Oxidation

oxidation

titanocene bis(trichloroacetate)

ASJC Scopus subject areas

Molecular Medicine

Cite this

Chan, T. R., Hilgraf, R., Sharpless, K. B., & Fokin, V. V. (2004). Polytriazoles as copper(I)-stabilizing ligands in catalysis. Organic Letters, 6(17), 2853-2855. https://doi.org/10.1021/ol0493094

Polytriazoles as copper(I)-stabilizing ligands in catalysis. / Chan, Timothy R.; Hilgraf, Robert; Sharpless, K. Barry; Fokin, Valery V.

In: Organic Letters, Vol. 6, No. 17, 19.08.2004, p. 2853-2855.

Research output: Contribution to journal › Article

Chan, TR, Hilgraf, R, Sharpless, KB & Fokin, VV 2004, 'Polytriazoles as copper(I)-stabilizing ligands in catalysis', Organic Letters, vol. 6, no. 17, pp. 2853-2855. https://doi.org/10.1021/ol0493094

Chan TR, Hilgraf R, Sharpless KB, Fokin VV. Polytriazoles as copper(I)-stabilizing ligands in catalysis. Organic Letters. 2004 Aug 19;6(17):2853-2855. https://doi.org/10.1021/ol0493094

Chan, Timothy R. ; Hilgraf, Robert ; Sharpless, K. Barry ; Fokin, Valery V. / Polytriazoles as copper(I)-stabilizing ligands in catalysis. In: Organic Letters. 2004 ; Vol. 6, No. 17. pp. 2853-2855.

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Access to Document

10.1021/ol0493094