Polysacharides Tussilagofarfara L. reduce myelosuppression induced by cisplatin and etoposide

E. A. Safonova, K. A. Lopatina, T. G. Razina, E. P. Fedorova, E. P. Zueva, A. M. Guriev, M. V. Belousov

Research School of Chemistry & Applied Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.

Original language	English
Pages (from-to)	42-48
Number of pages	7
Journal	Siberian Journal of Oncology
Volume	16
Issue number	4
DOIs	https://doi.org/10.21294/1814-4861-2017-16-4-42-48
Publication status	Published - 1 Jan 2017

Keywords

Chemotherapy
Cisplatin
Etoposide
Myelosuppression
Polysaccharides Tussilagofarfara L.

ASJC Scopus subject areas

Oncology
Cancer Research

Access to Document

10.21294/1814-4861-2017-16-4-42-48

Fingerprint Dive into the research topics of 'Polysacharides Tussilagofarfara L. reduce myelosuppression induced by cisplatin and etoposide'. Together they form a unique fingerprint.

Cite this

@article{8ca5a7f8805046bcb43bcb562b50b198,

title = "Polysacharides Tussilagofarfara L. reduce myelosuppression induced by cisplatin and etoposide",

abstract = "The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.",

keywords = "Chemotherapy, Cisplatin, Etoposide, Myelosuppression, Polysaccharides Tussilagofarfara L.",

author = "Safonova, {E. A.} and Lopatina, {K. A.} and Razina, {T. G.} and Fedorova, {E. P.} and Zueva, {E. P.} and Guriev, {A. M.} and Belousov, {M. V.}",

year = "2017",

month = jan,

day = "1",

doi = "10.21294/1814-4861-2017-16-4-42-48",

language = "English",

volume = "16",

pages = "42--48",

journal = "Siberian Journal of Oncology",

issn = "1814-4861",

publisher = "Tomsk National Research Medical Center of the Russian Academy of Sciences",

number = "4",

}

TY - JOUR

T1 - Polysacharides Tussilagofarfara L. reduce myelosuppression induced by cisplatin and etoposide

AU - Safonova, E. A.

AU - Lopatina, K. A.

AU - Razina, T. G.

AU - Fedorova, E. P.

AU - Zueva, E. P.

AU - Guriev, A. M.

AU - Belousov, M. V.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.

AB - The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.

KW - Chemotherapy

KW - Cisplatin

KW - Etoposide

KW - Myelosuppression

KW - Polysaccharides Tussilagofarfara L.

UR - http://www.scopus.com/inward/record.url?scp=85041583345&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041583345&partnerID=8YFLogxK

U2 - 10.21294/1814-4861-2017-16-4-42-48

DO - 10.21294/1814-4861-2017-16-4-42-48

M3 - Article

AN - SCOPUS:85041583345

VL - 16

SP - 42

EP - 48

JO - Siberian Journal of Oncology

JF - Siberian Journal of Oncology

SN - 1814-4861

IS - 4

ER -