Polysacharides Tussilagofarfara L. reduce myelosuppression induced by cisplatin and etoposide

E. A. Safonova, K. A. Lopatina, T. G. Razina, E. P. Fedorova, E. P. Zueva, A. M. Guriev, M. V. Belousov

Research School of Chemistry & Applied Biomedical Sciences

Research output: Contribution to journal › Article

Abstract

The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.

Original language	English
Pages (from-to)	42-48
Number of pages	7
Journal	Siberian Journal of Oncology
Volume	16
Issue number	4
DOIs	https://doi.org/10.21294/1814-4861-2017-16-4-42-48
Publication status	Published - 1 Jan 2017

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Keywords

Chemotherapy
Cisplatin
Etoposide
Myelosuppression
Polysaccharides Tussilagofarfara L.

ASJC Scopus subject areas

Oncology
Cancer Research

Cite this

Safonova, E. A., Lopatina, K. A., Razina, T. G., Fedorova, E. P., Zueva, E. P., Guriev, A. M., & Belousov, M. V. (2017). Polysacharides Tussilagofarfara L. reduce myelosuppression induced by cisplatin and etoposide. Siberian Journal of Oncology, 16(4), 42-48. https://doi.org/10.21294/1814-4861-2017-16-4-42-48

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abstract = "The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.",

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AU - Safonova, E. A.

AU - Lopatina, K. A.

AU - Razina, T. G.

AU - Fedorova, E. P.

AU - Zueva, E. P.

AU - Guriev, A. M.

AU - Belousov, M. V.

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KW - Etoposide

KW - Myelosuppression

KW - Polysaccharides Tussilagofarfara L.

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10.21294/1814-4861-2017-16-4-42-48