Polysaccharides of tussilago farfara L. As components of chemotherapy scheme

E. A. Safonova, K. A. Lopatina, E. P. Fedorova, O. Yu Rybalkina, T. G. Razina, A. M. Guriev, M. V. Belousov, E. P. Zueva

Research output: Contribution to journalArticle

Abstract

It was found that the addition of polysaccharides of Tussilago farfara L. to chemotherapy scheme "cisplatin + etoposide" lead to more pronounced inhibition of the Lewis lung carcinoma growth in mice due to the reduction of its mass in comparison with these parameters in animals treated according to the same scheme isolated. A use of polysaccharides of Tussilago farfara L. could reduce the hematotoxic effect of polychemotherapy with the "cisplatin + etoposide" scheme, which was expressed in a decrease of leukopenia and anemia.

Original languageEnglish
Pages (from-to)798-801
Number of pages4
JournalVoprosy Onkologii
Volume63
Issue number5
Publication statusPublished - 1 Jan 2017

Keywords

  • Cisplatin
  • Etoposide
  • Lewis lung carcinoma
  • Polychemotherapy
  • Polysaccharides

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Safonova, E. A., Lopatina, K. A., Fedorova, E. P., Rybalkina, O. Y., Razina, T. G., Guriev, A. M., Belousov, M. V., & Zueva, E. P. (2017). Polysaccharides of tussilago farfara L. As components of chemotherapy scheme. Voprosy Onkologii, 63(5), 798-801.