Polymer capsules modified with iron oxide nanoparticles as an effective platform for MRI visualization and drug delivery

L. I. Fatkhutdinova, A. Andreychenko, E. Brui, A. S. Timin, G. E. Pavlovskaya, A. N. Khlobystov, M. V. Zyuzin

Research output: Contribution to journalConference article

Abstract

Efficiency of existing (usually toxic) drugs can be increased substantially with the targeted effect on the site of the disease. A potential platform for the targeted drug delivery can be polymer capsules. This will help reduce side effects on the human body and start treatment at the early stages of the disease. Modification of such capsules with the magnetic nanoparticles allows their visualization using magnetic resonance imaging (MRI). In this study the use of polymer microcapsules modified with iron oxide nanoparticles are employed as contrast agents for T2-weighted magnetic resonance (MR) images, the possibility of their implementation as for drug delivery carriers are discussed. For this, two different types of polymer capsules are synthesized. The results on the spin-spin and spin-lattice relaxivities were obtained.

Original languageEnglish
Article number012037
JournalJournal of Physics: Conference Series
Volume1461
Issue number1
DOIs
Publication statusPublished - 23 Apr 2020
Event4th International Conference on Metamaterials and Nanophotonics, METANANO 2019 - St. Petersburg, Russian Federation
Duration: 15 Jul 201919 Jul 2019

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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