Platinum test in biological objects

N. A. Kolpakova, L. D. Ageeva, T. V. Kovyrkina

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

At the problematic lab of the Seversk Technological Institute of Tomsk Polytechnic University (STI TPU) two devices are used for heavy metals testing in biological objects: an analyzer (TA-1) which uses the method of inverse voltammetry (IV), and a spectrometer (Spectroskan) which uses the method of X-ray-fluorescence analysis (XFA). Professor N.A. Rolpakova (TPU, Chemical Engineering Faculty) uses the technique of platinum (Pt) test in biological materials (blood, urine, tissue) of patients having Pt treatment by an IV method was developed. Pt is used for treatment of oncological diseases. Its molecules bind the cells of a cancerous growth. To know the concentration of this drug in the blood of an oncological patient is necessary for overseeing a course of treatment. The essence of the method is the following: the Pt from assay is transferred to solution. The solution is placed in glass for polarographic measurement. The electrodes are inserted: an operating electrode (impregnated graphite electrode) and a comparison electrode (AgCl). During a definite time (the time of electrolysis) the Pt concentrates on the surface of an electrode together with mercury, which is beforehand entered in a parsed solution (metal-activator). The current of oxidation of the metal-activator, deposited together with Pt, is proportional to the content of Pt in the parsed assay. The content of Pt is determined by a method of standard components.

Original languageEnglish
Title of host publicationProceedings of the 6th International Scientific and Practical Conference of Students, Post-Graduates and Young Scientists: Modern Techniques and Technology, MTT 2000
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages205-207
Number of pages3
ISBN (Print)0780357892, 9780780357891
DOIs
Publication statusPublished - 2000
Event6th International Scientific and Practical Conference of Students, Post-Graduates and Young Scientists: Modern Techniques and Technology, MTT 2000 - Tomsk, Russian Federation
Duration: 28 Feb 20003 Mar 2000

Other

Other6th International Scientific and Practical Conference of Students, Post-Graduates and Young Scientists: Modern Techniques and Technology, MTT 2000
CountryRussian Federation
CityTomsk
Period28.2.003.3.00

ASJC Scopus subject areas

  • Engineering(all)

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