Abstract
Objectives. Inhaled nitric oxide treatment for ventilated premature infants improves survival without bronchopulmonary dysplasia. However, there has been no information regarding possible effects of this therapy on oxidative stress. We hypothesized that inhaled nitric oxide therapy would not influence concentrations of plasma biomarkers of oxidative stress. Patients and Methods. As part of the Nitric Oxide Chronic Lung Disease Trial, we collected blood samples at specified intervals from a subpopulation of 100 infants of
| Original language | English |
|---|---|
| Pages (from-to) | 555-561 |
| Number of pages | 7 |
| Journal | Pediatrics |
| Volume | 121 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2008 |
| Externally published | Yes |
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Keywords
- 3-nitrotyrosine
- Bronchopuimonary dysplasia
- Carbonyl
- Nitric oxide
- Premature infant
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Plasma biomarkers of oxidative stress : Relationship to lung disease and inhaled nitric oxide therapy in premature infants. / Ballard, Philip L.; Truog, William E.; Merrill, Jeffrey D.; Gow, Andrew; Posencheg, Michael; Golombek, Sergio G.; Parton, Lance A.; Luan, Xianqun; Cnaan, Avital; Ballard, Roberta A.
In: Pediatrics, Vol. 121, No. 3, 03.2008, p. 555-561.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasma biomarkers of oxidative stress
T2 - Relationship to lung disease and inhaled nitric oxide therapy in premature infants
AU - Ballard, Philip L.
AU - Truog, William E.
AU - Merrill, Jeffrey D.
AU - Gow, Andrew
AU - Posencheg, Michael
AU - Golombek, Sergio G.
AU - Parton, Lance A.
AU - Luan, Xianqun
AU - Cnaan, Avital
AU - Ballard, Roberta A.
PY - 2008/3
Y1 - 2008/3
N2 - Objectives. Inhaled nitric oxide treatment for ventilated premature infants improves survival without bronchopulmonary dysplasia. However, there has been no information regarding possible effects of this therapy on oxidative stress. We hypothesized that inhaled nitric oxide therapy would not influence concentrations of plasma biomarkers of oxidative stress. Patients and Methods. As part of the Nitric Oxide Chronic Lung Disease Trial, we collected blood samples at specified intervals from a subpopulation of 100 infants of
AB - Objectives. Inhaled nitric oxide treatment for ventilated premature infants improves survival without bronchopulmonary dysplasia. However, there has been no information regarding possible effects of this therapy on oxidative stress. We hypothesized that inhaled nitric oxide therapy would not influence concentrations of plasma biomarkers of oxidative stress. Patients and Methods. As part of the Nitric Oxide Chronic Lung Disease Trial, we collected blood samples at specified intervals from a subpopulation of 100 infants of
KW - 3-nitrotyrosine
KW - Bronchopuimonary dysplasia
KW - Carbonyl
KW - Nitric oxide
KW - Premature infant
UR - http://www.scopus.com/inward/record.url?scp=40949144900&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40949144900&partnerID=8YFLogxK
U2 - 10.1542/peds.2007-2479
DO - 10.1542/peds.2007-2479
M3 - Article
VL - 121
SP - 555
EP - 561
JO - Pediatrics
JF - Pediatrics
SN - 0031-4005
IS - 3
ER -