Plasma biomarkers of oxidative stress: Relationship to lung disease and inhaled nitric oxide therapy in premature infants

Philip L. Ballard, William E. Truog, Jeffrey D. Merrill, Andrew Gow, Michael Posencheg, Sergio G. Golombek, Lance A. Parton, Xianqun Luan, Avital Cnaan, Roberta A. Ballard

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Objectives. Inhaled nitric oxide treatment for ventilated premature infants improves survival without bronchopulmonary dysplasia. However, there has been no information regarding possible effects of this therapy on oxidative stress. We hypothesized that inhaled nitric oxide therapy would not influence concentrations of plasma biomarkers of oxidative stress. Patients and Methods. As part of the Nitric Oxide Chronic Lung Disease Trial, we collected blood samples at specified intervals from a subpopulation of 100 infants of

Original language	English
Pages (from-to)	555-561
Number of pages	7
Journal	Pediatrics
Volume	121
Issue number	3
DOIs	https://doi.org/10.1542/peds.2007-2479
Publication status	Published - Mar 2008
Externally published	Yes

Keywords

3-nitrotyrosine
Bronchopuimonary dysplasia
Carbonyl
Nitric oxide
Premature infant

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.1542/peds.2007-2479

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Plasma biomarkers of oxidative stress : Relationship to lung disease and inhaled nitric oxide therapy in premature infants. / Ballard, Philip L.; Truog, William E.; Merrill, Jeffrey D.; Gow, Andrew; Posencheg, Michael; Golombek, Sergio G.; Parton, Lance A.; Luan, Xianqun; Cnaan, Avital; Ballard, Roberta A.

In: Pediatrics, Vol. 121, No. 3, 03.2008, p. 555-561.

Research output: Contribution to journal › Article › peer-review

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