Piezoelectric polymer membranes with thin antibacterial coating for the regeneration of oral mucosa

A. D. Badaraev, A. Koniaeva, S. A. Krikova, E. V. Shesterikov, E. N. Bolbasov, A. L. Nemoykina, V. M. Bouznik, K. S. Stankevich, Y. M. Zhukov, I. P. Mishin, E. Y. Varakuta, S. I. Tverdokhlebov

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Herein, we have fabricated non-woven piezoelectric polymer membranes from a copolymer of vinylidene fluoride with tetrafluoroethylene by electrospinning for the regeneration of oral mucosa. In endeavor to make the antibacterial membranes, we have deposited a thin copper coating on the outer surface of the material via magnetron sputtering. The study of the physicochemical properties of membranes over the course of various plasma treatment times demonstrated that while coating deposition does not affect material physico-chemical properties, it allows making the membranes antibacterial. In vivo studies have shown that non-woven piezoelectric polymer membranes contribute to the oral mucosa regeneration and the copper antibacterial coating accelerates this process largely.

Original languageEnglish
Article number144068
JournalApplied Surface Science
Volume504
DOIs
Publication statusPublished - 28 Feb 2020

Keywords

  • Antibacterial activity
  • Copper
  • Magnetron sputtering
  • Oral mucosa
  • Polymer piezoelectric
  • Thin coatings
  • Tissue regeneration

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics
  • Physics and Astronomy(all)
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films

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