Physical properties and biocompatibility of UHMWPE-derived materials modified by synchrotron radiation

Iu Bykova, V. Weinhardt, A. Kashkarova, S. Lebedev, T. Baumbach, V. Pichugin, K. Zaitsev, Igor Albertovich Khlusov

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The applications of synchrotron radiation (SR) in medical imaging have become of great use, particularly in angiography, bronchography, mammography, computed tomography, and X-ray microscopy. Thanks to recently developed phase contrast imaging techniques non-destructive preclinical testing of low absorbing materials such as polymers has become possible. The focus of the present work is characterization and examination of UHMWPE-derived materials widely used in medicine, before and after their exposure to SR during such testing. Physical properties, such as wettability, surface energy, IR-spectroscopy, roughness, optical microscopy, microhardness measurements of UHMWPE samples were studied before and after SR. The relationship between a growth of UHMWPE surface hydrophilicity after SR and surface colonization by stromal cells was studied in vitro. Obtained results demonstrate that SR may be used as prospective direction to examine bulk (porous) structure of polymer materials and/or to modify polymer surface and volume for tissue engineering.

Original languageEnglish
Pages (from-to)1843-1852
Number of pages10
JournalJournal of Materials Science: Materials in Medicine
Volume25
Issue number8
DOIs
Publication statusPublished - 1 Jan 2014

Fingerprint

Synchrotrons
Ultrahigh molecular weight polyethylenes
Synchrotron radiation
Biocompatibility
Physical properties
Radiation
Polymers
Microscopy
Bronchography
Wettability
Mammography
Angiography
X Ray Computed Tomography
Medical imaging
Hydrophilicity
Diagnostic Imaging
Tissue Engineering
Stromal Cells
Nondestructive examination
Hydrophobic and Hydrophilic Interactions

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Cite this

Physical properties and biocompatibility of UHMWPE-derived materials modified by synchrotron radiation. / Bykova, Iu; Weinhardt, V.; Kashkarova, A.; Lebedev, S.; Baumbach, T.; Pichugin, V.; Zaitsev, K.; Khlusov, Igor Albertovich.

In: Journal of Materials Science: Materials in Medicine, Vol. 25, No. 8, 01.01.2014, p. 1843-1852.

Research output: Contribution to journalArticle

@article{7e8069ef3c5b4edb8a87a09ce95fb61a,
title = "Physical properties and biocompatibility of UHMWPE-derived materials modified by synchrotron radiation",
abstract = "The applications of synchrotron radiation (SR) in medical imaging have become of great use, particularly in angiography, bronchography, mammography, computed tomography, and X-ray microscopy. Thanks to recently developed phase contrast imaging techniques non-destructive preclinical testing of low absorbing materials such as polymers has become possible. The focus of the present work is characterization and examination of UHMWPE-derived materials widely used in medicine, before and after their exposure to SR during such testing. Physical properties, such as wettability, surface energy, IR-spectroscopy, roughness, optical microscopy, microhardness measurements of UHMWPE samples were studied before and after SR. The relationship between a growth of UHMWPE surface hydrophilicity after SR and surface colonization by stromal cells was studied in vitro. Obtained results demonstrate that SR may be used as prospective direction to examine bulk (porous) structure of polymer materials and/or to modify polymer surface and volume for tissue engineering.",
author = "Iu Bykova and V. Weinhardt and A. Kashkarova and S. Lebedev and T. Baumbach and V. Pichugin and K. Zaitsev and Igor Albertovich Khlusov",
year = "2014",
month = "1",
day = "1",
doi = "10.1007/s10856-014-5222-4",
language = "English",
volume = "25",
pages = "1843--1852",
journal = "Journal of Materials Science: Materials in Electronics",
issn = "0957-4530",
publisher = "Springer Netherlands",
number = "8",

}

TY - JOUR

T1 - Physical properties and biocompatibility of UHMWPE-derived materials modified by synchrotron radiation

AU - Bykova, Iu

AU - Weinhardt, V.

AU - Kashkarova, A.

AU - Lebedev, S.

AU - Baumbach, T.

AU - Pichugin, V.

AU - Zaitsev, K.

AU - Khlusov, Igor Albertovich

PY - 2014/1/1

Y1 - 2014/1/1

N2 - The applications of synchrotron radiation (SR) in medical imaging have become of great use, particularly in angiography, bronchography, mammography, computed tomography, and X-ray microscopy. Thanks to recently developed phase contrast imaging techniques non-destructive preclinical testing of low absorbing materials such as polymers has become possible. The focus of the present work is characterization and examination of UHMWPE-derived materials widely used in medicine, before and after their exposure to SR during such testing. Physical properties, such as wettability, surface energy, IR-spectroscopy, roughness, optical microscopy, microhardness measurements of UHMWPE samples were studied before and after SR. The relationship between a growth of UHMWPE surface hydrophilicity after SR and surface colonization by stromal cells was studied in vitro. Obtained results demonstrate that SR may be used as prospective direction to examine bulk (porous) structure of polymer materials and/or to modify polymer surface and volume for tissue engineering.

AB - The applications of synchrotron radiation (SR) in medical imaging have become of great use, particularly in angiography, bronchography, mammography, computed tomography, and X-ray microscopy. Thanks to recently developed phase contrast imaging techniques non-destructive preclinical testing of low absorbing materials such as polymers has become possible. The focus of the present work is characterization and examination of UHMWPE-derived materials widely used in medicine, before and after their exposure to SR during such testing. Physical properties, such as wettability, surface energy, IR-spectroscopy, roughness, optical microscopy, microhardness measurements of UHMWPE samples were studied before and after SR. The relationship between a growth of UHMWPE surface hydrophilicity after SR and surface colonization by stromal cells was studied in vitro. Obtained results demonstrate that SR may be used as prospective direction to examine bulk (porous) structure of polymer materials and/or to modify polymer surface and volume for tissue engineering.

UR - http://www.scopus.com/inward/record.url?scp=84904418604&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84904418604&partnerID=8YFLogxK

U2 - 10.1007/s10856-014-5222-4

DO - 10.1007/s10856-014-5222-4

M3 - Article

VL - 25

SP - 1843

EP - 1852

JO - Journal of Materials Science: Materials in Electronics

JF - Journal of Materials Science: Materials in Electronics

SN - 0957-4530

IS - 8

ER -