Physical properties and biocompatibility of UHMWPE-derived materials modified by synchrotron radiation

Iu Bykova, V. Weinhardt, A. Kashkarova, S. Lebedev, T. Baumbach, V. Pichugin, K. Zaitsev, Igor Albertovich Khlusov

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The applications of synchrotron radiation (SR) in medical imaging have become of great use, particularly in angiography, bronchography, mammography, computed tomography, and X-ray microscopy. Thanks to recently developed phase contrast imaging techniques non-destructive preclinical testing of low absorbing materials such as polymers has become possible. The focus of the present work is characterization and examination of UHMWPE-derived materials widely used in medicine, before and after their exposure to SR during such testing. Physical properties, such as wettability, surface energy, IR-spectroscopy, roughness, optical microscopy, microhardness measurements of UHMWPE samples were studied before and after SR. The relationship between a growth of UHMWPE surface hydrophilicity after SR and surface colonization by stromal cells was studied in vitro. Obtained results demonstrate that SR may be used as prospective direction to examine bulk (porous) structure of polymer materials and/or to modify polymer surface and volume for tissue engineering.

Original languageEnglish
Pages (from-to)1843-1852
Number of pages10
JournalJournal of Materials Science: Materials in Medicine
Volume25
Issue number8
DOIs
Publication statusPublished - 1 Jan 2014

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ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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