Abstract
Background: Light exposure of TPN generates peroxides which induce vasoconstriction. Mesenteric vasoconstriction may affect feeding tolerance. Since photo-protection of TPN decreases peroxide generation, we hypothesized that shielding TPN from light may improve the establishment of minimal enteral nutrition in preterm infants. Methods: Infants were randomized to TPN being light exposed (LE) or protected (LP) from birth. Feeding volumes were monitored through 7 days of life in those initiated on minimal enteral nutrition (MEN). Comparisons between LP and LE were performed by ANOVA. Results: Daily increments and cumulative volumes of enteral feeds (mL/kg birth weight/d) during the first week of life were significantly higher in LP (n = 18) than LE (n = 19). Conclusion: Photo-protection of parenteral nutrition enhances advancement of MEN in preterm infants. Further research is needed to substantiate these findings and determine whether this confers long-term nutritional advantages.
| Original language | English |
|---|---|
| Pages (from-to) | 139-145 |
| Number of pages | 7 |
| Journal | Seminars in Perinatology |
| Volume | 30 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jun 2006 |
| Externally published | Yes |
Fingerprint
Keywords
- minimal enteral nutrition
- newborn
- parenteral nutrition
- peroxides
- photoprotection
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Photoprotection of Parenteral Nutrition Enhances Advancement of Minimal Enteral Nutrition in Preterm Infants. / Khashu, Minesh; Harrison, Adele; Lalari, Vikki; Gow, Andrew; Lavoie, Jean Claude; Chessex, Philippe.
In: Seminars in Perinatology, Vol. 30, No. 3, 06.2006, p. 139-145.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Photoprotection of Parenteral Nutrition Enhances Advancement of Minimal Enteral Nutrition in Preterm Infants
AU - Khashu, Minesh
AU - Harrison, Adele
AU - Lalari, Vikki
AU - Gow, Andrew
AU - Lavoie, Jean Claude
AU - Chessex, Philippe
PY - 2006/6
Y1 - 2006/6
N2 - Background: Light exposure of TPN generates peroxides which induce vasoconstriction. Mesenteric vasoconstriction may affect feeding tolerance. Since photo-protection of TPN decreases peroxide generation, we hypothesized that shielding TPN from light may improve the establishment of minimal enteral nutrition in preterm infants. Methods: Infants were randomized to TPN being light exposed (LE) or protected (LP) from birth. Feeding volumes were monitored through 7 days of life in those initiated on minimal enteral nutrition (MEN). Comparisons between LP and LE were performed by ANOVA. Results: Daily increments and cumulative volumes of enteral feeds (mL/kg birth weight/d) during the first week of life were significantly higher in LP (n = 18) than LE (n = 19). Conclusion: Photo-protection of parenteral nutrition enhances advancement of MEN in preterm infants. Further research is needed to substantiate these findings and determine whether this confers long-term nutritional advantages.
AB - Background: Light exposure of TPN generates peroxides which induce vasoconstriction. Mesenteric vasoconstriction may affect feeding tolerance. Since photo-protection of TPN decreases peroxide generation, we hypothesized that shielding TPN from light may improve the establishment of minimal enteral nutrition in preterm infants. Methods: Infants were randomized to TPN being light exposed (LE) or protected (LP) from birth. Feeding volumes were monitored through 7 days of life in those initiated on minimal enteral nutrition (MEN). Comparisons between LP and LE were performed by ANOVA. Results: Daily increments and cumulative volumes of enteral feeds (mL/kg birth weight/d) during the first week of life were significantly higher in LP (n = 18) than LE (n = 19). Conclusion: Photo-protection of parenteral nutrition enhances advancement of MEN in preterm infants. Further research is needed to substantiate these findings and determine whether this confers long-term nutritional advantages.
KW - minimal enteral nutrition
KW - newborn
KW - parenteral nutrition
KW - peroxides
KW - photoprotection
UR - http://www.scopus.com/inward/record.url?scp=33745264371&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33745264371&partnerID=8YFLogxK
U2 - 10.1053/j.semperi.2006.04.007
DO - 10.1053/j.semperi.2006.04.007
M3 - Review article
C2 - 16813972
AN - SCOPUS:33745264371
VL - 30
SP - 139
EP - 145
JO - Seminars in Perinatology
JF - Seminars in Perinatology
SN - 0146-0005
IS - 3
ER -