Photoacoustic spectroscopy of the expired air at a human respiratory pathology

B. G. Ageev, V. A. Kapitanov, Yu N. Ponomarev, O. Yu Nikiforova, A. I. Karapuzikov, I. V. Sherstov, L. I. Volkova, E. Yu Djakova, L. V. Kapilevich, D. V. Kapitanova, Yu V. Kistenev, N. A. Smotrova, V. A. Fokin, A. V. Plohotin, T. A. Berendeeva

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

There are about 600 volatile compounds in air expired by man, including molecules-biomarkers of endogenous (produced in organism) origin, the specificity of generation and excretion mechanisms of which is sufficient for studies of both normal and pathologic processes. The goal of this work is analysis of the human-expired air by means of the intracavity laser photoacoustic sensor intended for detection of air gas admixtures having the absorption bands in the wavelength spectral range 9.2 - 10.8 μm. The sensor principle of operation is based on the photoacoustic effect caused by gas absorption of the CO2 laser radiation. Measurements were conducted with a test group consisting of 100 persons and a group of patients (60 persons) affected by different bronchopulmonary pathologies. The state of health of each group members was determined from questioning data. The spectral absorption dependences were normalized to referent points and then investigated in respect to a qualitative coincidence. The typical results are presented below.

Original languageEnglish
Title of host publication15th Symposium on High-Resolution Molecular Spectroscopy
DOIs
Publication statusPublished - 2006
Event15th Symposium on High-Resolution Molecular Spectroscopy - Nizhny Novgorod, Russian Federation
Duration: 18 Jul 200621 Jul 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6580
ISSN (Print)0277-786X

Conference

Conference15th Symposium on High-Resolution Molecular Spectroscopy
CountryRussian Federation
CityNizhny Novgorod
Period18.7.0621.7.06

Keywords

  • Absorption spectrum
  • CO laser
  • Expired air
  • Gases-biomarkers
  • Photoacoustic spectroscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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