Abstract
Cholinergic contractile reactions of smooth muscles in rabbit pulmonary arteries were studied by mechanography. The muscarinic receptor agonist pilocarpine induced biphasic relaxation of mesatone- or potassium-precontracted segments from lobar pulmonary arteries with intact endothelium. The low-threshold endothelium-dependent component of pilocarpine-induced relaxation was suppressed by denudation or nitric oxide synthase blocker L-NAME.
| Original language | English |
|---|---|
| Pages (from-to) | 728-730 |
| Number of pages | 3 |
| Journal | Bulletin of Experimental Biology and Medicine |
| Volume | 130 |
| Issue number | 8 |
| Publication status | Published - 2000 |
| Externally published | Yes |
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Keywords
- Endothelium
- Nitric oxide
- Pulmonary arteries
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Kapilevich, L. V., Anfinogenova, Y. J., Baskakov, M. B., Kovalec, I. V., Nosarev, A. V., & Medvedev, M. A. (2000). Peculiarities of cholinergic regulation of smooth muscles in rabbit pulmonary arteries. Bulletin of Experimental Biology and Medicine, 130(8), 728-730.