Cholinergic contractile reactions of smooth muscles in rabbit pulmonary arteries were studied by mechanography. The muscarinic receptor agonist pilocarpine induced biphasic relaxation of mesatone- or potassium-precontracted segments from lobar pulmonary arteries with intact endothelium. The low-threshold endothelium-dependent component of pilocarpine-induced relaxation was suppressed by denudation or nitric oxide synthase blocker L-NAME.
|Number of pages||3|
|Journal||Bulletin of Experimental Biology and Medicine|
|Publication status||Published - 2000|
- Nitric oxide
- Pulmonary arteries
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)