Abstract
Cholinergic contractile reactions of smooth muscles in rabbit pulmonary arteries were studied by mechanography. The muscarinic receptor agonist pilocarpine induced biphasic relaxation of mesatone- or potassium-precontracted segments from lobar pulmonary arteries with intact endothelium. The low-threshold endothelium-dependent component of pilocarpine-induced relaxation was suppressed by denudation or nitric oxide synthase blocker L-NAME.
| Original language | English |
|---|---|
| Pages (from-to) | 728-730 |
| Number of pages | 3 |
| Journal | Bulletin of Experimental Biology and Medicine |
| Volume | 130 |
| Issue number | 8 |
| Publication status | Published - 2000 |
| Externally published | Yes |
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Keywords
- Endothelium
- Nitric oxide
- Pulmonary arteries
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Peculiarities of cholinergic regulation of smooth muscles in rabbit pulmonary arteries. / Kapilevich, L. V.; Anfinogenova, Yana Jonovna; Baskakov, M. B.; Kovalec, I. V.; Nosarev, A. V.; Medvedev, M. A.
In: Bulletin of Experimental Biology and Medicine, Vol. 130, No. 8, 2000, p. 728-730.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peculiarities of cholinergic regulation of smooth muscles in rabbit pulmonary arteries
AU - Kapilevich, L. V.
AU - Anfinogenova, Yana Jonovna
AU - Baskakov, M. B.
AU - Kovalec, I. V.
AU - Nosarev, A. V.
AU - Medvedev, M. A.
PY - 2000
Y1 - 2000
N2 - Cholinergic contractile reactions of smooth muscles in rabbit pulmonary arteries were studied by mechanography. The muscarinic receptor agonist pilocarpine induced biphasic relaxation of mesatone- or potassium-precontracted segments from lobar pulmonary arteries with intact endothelium. The low-threshold endothelium-dependent component of pilocarpine-induced relaxation was suppressed by denudation or nitric oxide synthase blocker L-NAME.
AB - Cholinergic contractile reactions of smooth muscles in rabbit pulmonary arteries were studied by mechanography. The muscarinic receptor agonist pilocarpine induced biphasic relaxation of mesatone- or potassium-precontracted segments from lobar pulmonary arteries with intact endothelium. The low-threshold endothelium-dependent component of pilocarpine-induced relaxation was suppressed by denudation or nitric oxide synthase blocker L-NAME.
KW - Endothelium
KW - Nitric oxide
KW - Pulmonary arteries
UR - http://www.scopus.com/inward/record.url?scp=0035122512&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035122512&partnerID=8YFLogxK
M3 - Article
C2 - 11177226
AN - SCOPUS:0035122512
VL - 130
SP - 728
EP - 730
JO - Bulletin of Experimental Biology and Medicine
JF - Bulletin of Experimental Biology and Medicine
SN - 0007-4888
IS - 8
ER -