Participation of inducible stress proteins in the cardioprotective effect of Rhodiolae rosea

S. A. Afanas'ev, A. V. Krylatov, T. V. Lasukova, Yu B. Lishmanov

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Effects of the Rhodiolae rosea extract on the contractility of rat hearts isolated by the method of Langendorff, the activity of creatine phosphokinase in the perfusate, and the induction of synthesis of stress proteins in the myocardium were studied after total ischemia and reperfusion. This adaptogen produced a cardioprotective effect and prevented a disturbance of contractility due to ischemia and reperfusion. The possible participation of the inducible stress proteins (hsp-70) in these effects is discussed.

Original languageEnglish
Pages (from-to)1258-1261
Number of pages4
JournalBiochemistry (Moscow)
Volume61
Issue number10
Publication statusPublished - 1996

Keywords

  • Adaptation
  • Ischemia
  • Isolated heart
  • Myocardial stress proteins
  • Reoxygenation
  • Rhodiolae rosea

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

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