Palladium-catalyzed synthesis of aryl ketones from boronic acids and carboxylic acids or anhydrides

Valery V. Fokin, K. Barry Sharpless

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Mild and convenient: A palladium-catalyzed cross-coupling reaction between arylboronic acids and carboxylic anhydrides, which are generated in situ from the corresponding carboxylic acids, allows the efficient synthesis of a broad variety of functionalized aryl ketones [Eq. (1)].

Original languageEnglish
Pages (from-to)3458-3460
Number of pages3
JournalAngewandte Chemie - International Edition
Volume40
Issue number18
DOIs
Publication statusPublished - 17 Sep 2001
Externally publishedYes

Keywords

  • Boronic acids
  • Carboxylic acids
  • Homogeneous catalysis
  • Ketones
  • Palladium

ASJC Scopus subject areas

  • Chemistry(all)

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