Osteoblast ingrowth into titanium scaffolds made by electron beam melting

Andrey Koptyug, Claudia Bergemann, Regina Lange, Victor Emanuel Jaggi, Lars Erik Rännar, J. Barbara Nebe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Present paper describes early findings from the study of Ti-6Al-4V scaffolds additively manufactured using electron beam melting (EBM®) technology and the influence of surface topography on the initial stages of cell acceptance. The surface topography of the components made by additive manufacturing (AM) processes including EBM® are often hard to control within the desired feature size range without post-processing. Two groups of experiments studying the behavior of human osteoblast-like cells (MG63) on samples with different surface roughness were carried out in vitro: Ti-6Al-4V samples only powder-blasted, and Ti-6Al-4V samples additionally electrochemically polished. The cell migration into powder-blasted Ti-6Al-4V 3D scaffolds with different shapes and dimensions of the lattice structures were studied.

Original languageEnglish
Title of host publicationTHERMEC 2013
EditorsB. Mishra, Mihail. Ionescu, T. Chandra
PublisherTrans Tech Publications Ltd
Pages1292-1297
Number of pages6
ISBN (Print)9783038350736
Publication statusPublished - 2014
Externally publishedYes
Event8th International Conference on Processing and Manufacturing of Advanced Materials, THERMEC 2013 - Las Vegas, NV, United States
Duration: 2 Dec 20136 Dec 2013

Publication series

NameMaterials Science Forum
Volume783-786
ISSN (Print)0255-5476
ISSN (Electronic)1662-9752

Conference

Conference8th International Conference on Processing and Manufacturing of Advanced Materials, THERMEC 2013
CountryUnited States
CityLas Vegas, NV
Period2.12.136.12.13

Keywords

  • 3D cell culture
  • Additive manufacturing
  • Biocompatibility
  • Electron beam melting
  • Osteoblastic cells
  • RT-PCR
  • Scaffold
  • Surface roughness
  • Titanium

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Osteoblast ingrowth into titanium scaffolds made by electron beam melting'. Together they form a unique fingerprint.

Cite this