Osseointegration of sputtered SiC-added hydroxyapatite for orthopaedic applications

D. M. Vranceanu, C. M. Cotrut, M. Bramowicz, I. Titorencu, S. Kulesza, A. Kiss, A. Berbecaru, V. Pruna, M. Branzei, A. Vladescu

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Over the last few years, a trend in medical applications is to find solutions for metallic implants using coatings that can improve bioactivity and osseointegration. The goal of this study was to obtain and investigate sputtered hydroxyapatite coatings enriched with SiC to enhance the bioactivity and osseointegration of Ti alloys used in orthopaedic applications. The films were characterized in terms of phase composition, roughness, corrosion resistance in a synthetic body fluid (SBF) and in vitro biocompatibility with MG 63 osteoblast-like cells. All of the investigations were conducted using XRD, AFM, cell viability assays and proliferation tests. The results revealed that the addition of SiC had a positive influence on the properties of the sputtered hydroxyapatite. The addition of SiC led to an improvement in coating adhesion and corrosion resistance in an SBF solution over the HAP coating. All of the coatings presented cell viability values over 90%, revealing their suitability for medical applications.

Original languageEnglish
Pages (from-to)10085-10093
Number of pages9
JournalCeramics International
Volume42
Issue number8
DOIs
Publication statusPublished - 1 Jun 2016
Externally publishedYes

Fingerprint

Orthopedics
Durapatite
Hydroxyapatite
Coatings
Body fluids
Medical applications
Bioactivity
Corrosion resistance
Cells
Osteoblasts
Biocompatibility
Phase composition
Assays
Adhesion
Surface roughness

Keywords

  • B: Porosity
  • C: Corrosion
  • D: Apatite
  • E: Biomedical applications

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Process Chemistry and Technology
  • Surfaces, Coatings and Films
  • Materials Chemistry

Cite this

Osseointegration of sputtered SiC-added hydroxyapatite for orthopaedic applications. / Vranceanu, D. M.; Cotrut, C. M.; Bramowicz, M.; Titorencu, I.; Kulesza, S.; Kiss, A.; Berbecaru, A.; Pruna, V.; Branzei, M.; Vladescu, A.

In: Ceramics International, Vol. 42, No. 8, 01.06.2016, p. 10085-10093.

Research output: Contribution to journalArticle

Vranceanu, DM, Cotrut, CM, Bramowicz, M, Titorencu, I, Kulesza, S, Kiss, A, Berbecaru, A, Pruna, V, Branzei, M & Vladescu, A 2016, 'Osseointegration of sputtered SiC-added hydroxyapatite for orthopaedic applications', Ceramics International, vol. 42, no. 8, pp. 10085-10093. https://doi.org/10.1016/j.ceramint.2016.03.114
Vranceanu, D. M. ; Cotrut, C. M. ; Bramowicz, M. ; Titorencu, I. ; Kulesza, S. ; Kiss, A. ; Berbecaru, A. ; Pruna, V. ; Branzei, M. ; Vladescu, A. / Osseointegration of sputtered SiC-added hydroxyapatite for orthopaedic applications. In: Ceramics International. 2016 ; Vol. 42, No. 8. pp. 10085-10093.
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AB - Over the last few years, a trend in medical applications is to find solutions for metallic implants using coatings that can improve bioactivity and osseointegration. The goal of this study was to obtain and investigate sputtered hydroxyapatite coatings enriched with SiC to enhance the bioactivity and osseointegration of Ti alloys used in orthopaedic applications. The films were characterized in terms of phase composition, roughness, corrosion resistance in a synthetic body fluid (SBF) and in vitro biocompatibility with MG 63 osteoblast-like cells. All of the investigations were conducted using XRD, AFM, cell viability assays and proliferation tests. The results revealed that the addition of SiC had a positive influence on the properties of the sputtered hydroxyapatite. The addition of SiC led to an improvement in coating adhesion and corrosion resistance in an SBF solution over the HAP coating. All of the coatings presented cell viability values over 90%, revealing their suitability for medical applications.

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