Opioid receptors and heart resistance to arrhythmogenic factors

Yu B. Lishmanov, L. N. Maslov

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)

Abstract

We present detailed data on the role of central and peripheral opioid receptors in the regulation of heart resistance to arrhythmogenic factors. Stimulation of peripheral δ2- and κ1-receptors increases heart resistance to the arrhythmogenic effect of acute ischemia and reperfusion. Activation of peripheral μ- and δ1-opioid receptors improves electrical stability of the heart in animals with postinfarction cardiosclerosis. Possible mechanisms for opioidergic regulation of heart resistance to arrhythmogenic factors are discussed.

Original languageEnglish
Pages (from-to)107-112
Number of pages6
JournalBulletin of Experimental Biology and Medicine
Volume138
Issue number2
DOIs
Publication statusPublished - 1 Aug 2004

Keywords

  • Arrhythmogenesis
  • cardiac ischemia/reperfusion
  • Opioid receptors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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