One-step synthesis of stereo-pure L,L lactide from L-lactic acid

Marzieh Ghadamyari, Somboon Chaemchuen, Kui Zhou, Michiel Dusselier, Bert F. Sels, Bibimaryam Mousavi, Francis Verpoort

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Poly (lactic acid) (PLA) is extensively used as an eco-friendly compound for many applications. The synthesis of stereo-pure lactide, specifically L,L-lactide which is the most desired isomer for the synthesis of high-quality PLA is very important. In this work, various materials including MOFs and simple bases have been applied as catalysts for the Lactide synthesis. Herein we report the one-step synthesis of L,L-lactide with high selectivity and yield (99%) in the absence of racemization by applying a cost-effective Cs2CO3 catalyst. The novel described procedure is even expected to be very efficient for industrial applications.

Original languageEnglish
Pages (from-to)33-36
Number of pages4
JournalCatalysis Communications
Publication statusPublished - 1 Aug 2018


  • Cesium carbonate
  • Lactic acid
  • Lactide
  • MOFs
  • Poly lactic acid

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Process Chemistry and Technology

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