One-pot synthesis of monosubstituted aryl(hetaryl)acetylenes by direct introduction of the C≡CH residue into arenes and hetarenes

Sergei F. Vasilevsky, Svetlana V. Klyatskaya, José Elguero

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A convenient one-pot synthesis of aryl(hetaryl)acetylenes by cross-coupling of aryl(hetaryl)iodides with acetylene in presence of PdCl2(Ph 3)2, CuI and K2CO3 in DMF has been developed.

Original languageEnglish
Pages (from-to)6685-6688
Number of pages4
JournalTetrahedron
Volume60
Issue number31
DOIs
Publication statusPublished - 26 Jul 2004
Externally publishedYes

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Keywords

  • Cross-coupling
  • Homogeneous catalysis
  • Monosubstituted acetylenes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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