On the involvement of endogenous μ- and δ-opiate receptor agonists in the antiarrhythmic effect of adaptation

L. N. Maslov, A. V. Krylatov, Yu B. Lishmanov

Research Nuclear Reactor Center

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Abstract

Rats adapted to stress showed a decreased severity and incidence of cardiac arrhythmias induced by epinephrine, and these effects of adaptation were abolished by naloxone. It is suggested that stress adaptation mitigates arrhythmia by activating the endogenous opioid system and stimulating the μ-opiate receptors.

Original language	English
Pages (from-to)	20-21
Number of pages	2
Journal	Bulletin of Experimental Biology and Medicine
Volume	121
Issue number	1
Publication status	Published - Jan 1996

Keywords

Adaptation
Arrhythmia
Opiate receptors
Stress

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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abstract = "Rats adapted to stress showed a decreased severity and incidence of cardiac arrhythmias induced by epinephrine, and these effects of adaptation were abolished by naloxone. It is suggested that stress adaptation mitigates arrhythmia by activating the endogenous opioid system and stimulating the μ-opiate receptors.",

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