On-line microfluidic sers measurements on the base of surface plasmonpolariton excitation

Vasilii Burtsev, Elena Miliutina, Olga Guselnikova, Vaclav Vorcik, Oleksiy Lyutakov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

There are many methods that allow detection of complex analytes such as soil contaminants and explosives, which can be dispersed in the various of liquid and solid. Nevertheless, it remains a challenge to create a labon-a-chip (LoC) platform for on-line detection of small analytes volumes (below the few femtoliters), with high sensitivity, specificity and reliability. It is expected that the combination of microfluidics and plasmonic will create a highly sensitive and affordable lab-on-a-chip platform for the solving of above mentioned challenge. The proposed approach will utilize the unique advantages of microfluidics that explore and uses unusual behavior of microscale-restricted liquids and surface-enhanced Raman analytical method, which is able to recognize the single molecule of the targeted analyte. In this work, we demonstrated the model of a microfluidic micromixer incorporating with a plasmon active substrate. The design and realization of proposed experimental concept include the solving of following tasks: (i) utilization of Comsol software for mathematical simulation of possible processes in microfluidic mixer; (II) preparation of microfluidic platform using 3D printing; (III) application of excimer UV laser large-scale patterning and local gold deposition for creation of plasmonic active area. Our LoC platform allows detection of model analyte (R6G) at concentrations down to 10 fM (10-15 mol·L-1). Proposed unique features are the key to new scientific experiments and innovations in the field of labon-a-chip devices and analytical approaches.

Original languageEnglish
Title of host publicationNANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application
PublisherTANGER Ltd.
Pages725-729
Number of pages5
ISBN (Electronic)9788087294895
Publication statusPublished - 1 Jan 2019
Event10th Anniversary International Conference on Nanomaterials - Research and Application, NANOCON 2018 - Brno, Czech Republic
Duration: 17 Oct 201819 Oct 2018

Publication series

NameNANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application

Conference

Conference10th Anniversary International Conference on Nanomaterials - Research and Application, NANOCON 2018
CountryCzech Republic
CityBrno
Period17.10.1819.10.18

    Fingerprint

Keywords

  • 3D printing
  • Lab-on-a-chip
  • Microfluidics system
  • R6G
  • SERS

ASJC Scopus subject areas

  • Biotechnology
  • Electrical and Electronic Engineering
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials

Cite this

Burtsev, V., Miliutina, E., Guselnikova, O., Vorcik, V., & Lyutakov, O. (2019). On-line microfluidic sers measurements on the base of surface plasmonpolariton excitation. In NANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application (pp. 725-729). (NANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application). TANGER Ltd..