@inproceedings{44526d518e5d4a29a5f3ebc5f819ed34,
title = "On-line microfluidic sers measurements on the base of surface plasmonpolariton excitation",
abstract = "There are many methods that allow detection of complex analytes such as soil contaminants and explosives, which can be dispersed in the various of liquid and solid. Nevertheless, it remains a challenge to create a labon-a-chip (LoC) platform for on-line detection of small analytes volumes (below the few femtoliters), with high sensitivity, specificity and reliability. It is expected that the combination of microfluidics and plasmonic will create a highly sensitive and affordable lab-on-a-chip platform for the solving of above mentioned challenge. The proposed approach will utilize the unique advantages of microfluidics that explore and uses unusual behavior of microscale-restricted liquids and surface-enhanced Raman analytical method, which is able to recognize the single molecule of the targeted analyte. In this work, we demonstrated the model of a microfluidic micromixer incorporating with a plasmon active substrate. The design and realization of proposed experimental concept include the solving of following tasks: (i) utilization of Comsol software for mathematical simulation of possible processes in microfluidic mixer; (II) preparation of microfluidic platform using 3D printing; (III) application of excimer UV laser large-scale patterning and local gold deposition for creation of plasmonic active area. Our LoC platform allows detection of model analyte (R6G) at concentrations down to 10 fM (10-15 mol·L-1). Proposed unique features are the key to new scientific experiments and innovations in the field of labon-a-chip devices and analytical approaches.",
keywords = "3D printing, Lab-on-a-chip, Microfluidics system, R6G, SERS",
author = "Vasilii Burtsev and Elena Miliutina and Olga Guselnikova and Vaclav Vorcik and Oleksiy Lyutakov",
year = "2019",
month = jan,
day = "1",
language = "English",
series = "NANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application",
publisher = "TANGER Ltd.",
pages = "725--729",
booktitle = "NANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application",
note = "10th Anniversary International Conference on Nanomaterials - Research and Application, NANOCON 2018 ; Conference date: 17-10-2018 Through 19-10-2018",
}