Abstract
ortho-Fluorbenzoic acid (FBA) is useful product for organic syntheses and preparation of some medicines. We have elaborated the following effective chemical methods for synthesis of FBA. i) Nucleophilic substitution of o-chlorobenzoic acid by action of KF in the presence of the crown-ethers or inter-phase catalysis; ii) Reaction of anthranilic acid with NaNO2 into liquid HF with following thermal decomposition of the resulted diazonium salt at 100°C; iii) Fluorodecarboxilation of phthalic acid or its anhydride by heating in benzene in the presence of Pb(OAc)4 and CaF2. Also we have designed and produced of a special reactor for an electrochemical fluorination of various organic compounds.
| Original language | English |
|---|---|
| Title of host publication | Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 173-175 |
| Number of pages | 3 |
| Volume | 1 |
| ISBN (Print) | 0780364864, 9780780364868 |
| DOIs | |
| Publication status | Published - 2000 |
| Event | 4th Korea-Russia International Symposium on Science and Technology, KORUS 2000 - Ulsan, Korea, Republic of Duration: 27 Jun 2000 → 1 Jul 2000 |
Other
| Other | 4th Korea-Russia International Symposium on Science and Technology, KORUS 2000 |
|---|---|
| Country | Korea, Republic of |
| City | Ulsan |
| Period | 27.6.00 → 1.7.00 |
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Keywords
- electrosynthesis
- fluorbenzoic acid
- fluorination
ASJC Scopus subject areas
- Clinical Biochemistry
- Computer Networks and Communications
- Biotechnology
- Civil and Structural Engineering
- Mechanics of Materials
- Electronic, Optical and Magnetic Materials
- Materials Chemistry
- Surfaces, Coatings and Films
Cite this
Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds. / Murlushev, A. P.; Loshkomoev, S. N.; Tomash, Y. Ya; Kobzar, Y. F.; Zherin, I. I.; Arbit, G. A.; Filimonov, V. D.
Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology. Vol. 1 Institute of Electrical and Electronics Engineers Inc., 2000. p. 173-175 865945.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds
AU - Murlushev, A. P.
AU - Loshkomoev, S. N.
AU - Tomash, Y. Ya
AU - Kobzar, Y. F.
AU - Zherin, I. I.
AU - Arbit, G. A.
AU - Filimonov, V. D.
PY - 2000
Y1 - 2000
N2 - ortho-Fluorbenzoic acid (FBA) is useful product for organic syntheses and preparation of some medicines. We have elaborated the following effective chemical methods for synthesis of FBA. i) Nucleophilic substitution of o-chlorobenzoic acid by action of KF in the presence of the crown-ethers or inter-phase catalysis; ii) Reaction of anthranilic acid with NaNO2 into liquid HF with following thermal decomposition of the resulted diazonium salt at 100°C; iii) Fluorodecarboxilation of phthalic acid or its anhydride by heating in benzene in the presence of Pb(OAc)4 and CaF2. Also we have designed and produced of a special reactor for an electrochemical fluorination of various organic compounds.
AB - ortho-Fluorbenzoic acid (FBA) is useful product for organic syntheses and preparation of some medicines. We have elaborated the following effective chemical methods for synthesis of FBA. i) Nucleophilic substitution of o-chlorobenzoic acid by action of KF in the presence of the crown-ethers or inter-phase catalysis; ii) Reaction of anthranilic acid with NaNO2 into liquid HF with following thermal decomposition of the resulted diazonium salt at 100°C; iii) Fluorodecarboxilation of phthalic acid or its anhydride by heating in benzene in the presence of Pb(OAc)4 and CaF2. Also we have designed and produced of a special reactor for an electrochemical fluorination of various organic compounds.
KW - electrosynthesis
KW - fluorbenzoic acid
KW - fluorination
UR - http://www.scopus.com/inward/record.url?scp=84960848160&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84960848160&partnerID=8YFLogxK
U2 - 10.1109/KORUS.2000.865945
DO - 10.1109/KORUS.2000.865945
M3 - Conference contribution
AN - SCOPUS:84960848160
SN - 0780364864
SN - 9780780364868
VL - 1
SP - 173
EP - 175
BT - Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology
PB - Institute of Electrical and Electronics Engineers Inc.
ER -