Abstract
ortho-Fluorbenzoic acid (FBA) is useful product for organic syntheses and preparation of some medicines. We have elaborated the following effective chemical methods for synthesis of FBA. i) Nucleophilic substitution of o-chlorobenzoic acid by action of KF in the presence of the crown-ethers or inter-phase catalysis; ii) Reaction of anthranilic acid with NaNO2 into liquid HF with following thermal decomposition of the resulted diazonium salt at 100°C; iii) Fluorodecarboxilation of phthalic acid or its anhydride by heating in benzene in the presence of Pb(OAc)4 and CaF2. Also we have designed and produced of a special reactor for an electrochemical fluorination of various organic compounds.
Original language | English |
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Title of host publication | Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 173-175 |
Number of pages | 3 |
Volume | 1 |
ISBN (Print) | 0780364864, 9780780364868 |
DOIs | |
Publication status | Published - 2000 |
Event | 4th Korea-Russia International Symposium on Science and Technology, KORUS 2000 - Ulsan, Korea, Republic of Duration: 27 Jun 2000 → 1 Jul 2000 |
Other
Other | 4th Korea-Russia International Symposium on Science and Technology, KORUS 2000 |
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Country | Korea, Republic of |
City | Ulsan |
Period | 27.6.00 → 1.7.00 |
Keywords
- electrosynthesis
- fluorbenzoic acid
- fluorination
ASJC Scopus subject areas
- Clinical Biochemistry
- Computer Networks and Communications
- Biotechnology
- Civil and Structural Engineering
- Mechanics of Materials
- Electronic, Optical and Magnetic Materials
- Materials Chemistry
- Surfaces, Coatings and Films