Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds

A. P. Murlushev, S. N. Loshkomoev, Y. Ya Tomash, Y. F. Kobzar, I. I. Zherin, G. A. Arbit, V. D. Filimonov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

ortho-Fluorbenzoic acid (FBA) is useful product for organic syntheses and preparation of some medicines. We have elaborated the following effective chemical methods for synthesis of FBA. i) Nucleophilic substitution of o-chlorobenzoic acid by action of KF in the presence of the crown-ethers or inter-phase catalysis; ii) Reaction of anthranilic acid with NaNO2 into liquid HF with following thermal decomposition of the resulted diazonium salt at 100°C; iii) Fluorodecarboxilation of phthalic acid or its anhydride by heating in benzene in the presence of Pb(OAc)4 and CaF2. Also we have designed and produced of a special reactor for an electrochemical fluorination of various organic compounds.

Original languageEnglish
Title of host publicationProceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages173-175
Number of pages3
Volume1
ISBN (Print)0780364864, 9780780364868
DOIs
Publication statusPublished - 2000
Event4th Korea-Russia International Symposium on Science and Technology, KORUS 2000 - Ulsan, Korea, Republic of
Duration: 27 Jun 20001 Jul 2000

Other

Other4th Korea-Russia International Symposium on Science and Technology, KORUS 2000
CountryKorea, Republic of
CityUlsan
Period27.6.001.7.00

Fingerprint

Chlorobenzoates
Crown Ethers
Synthetic Chemistry Techniques
Fluorination
Acids
Anhydrides
Halogenation
Benzene
Catalysis
Organic compounds
Heating
Medicine
Pyrolysis
Substitution reactions
Salts
Hot Temperature
Liquids
Crown ethers
phthalic acid
anthranilic acid

Keywords

  • electrosynthesis
  • fluorbenzoic acid
  • fluorination

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Computer Networks and Communications
  • Biotechnology
  • Civil and Structural Engineering
  • Mechanics of Materials
  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Surfaces, Coatings and Films

Cite this

Murlushev, A. P., Loshkomoev, S. N., Tomash, Y. Y., Kobzar, Y. F., Zherin, I. I., Arbit, G. A., & Filimonov, V. D. (2000). Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds. In Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology (Vol. 1, pp. 173-175). [865945] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/KORUS.2000.865945

Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds. / Murlushev, A. P.; Loshkomoev, S. N.; Tomash, Y. Ya; Kobzar, Y. F.; Zherin, I. I.; Arbit, G. A.; Filimonov, V. D.

Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology. Vol. 1 Institute of Electrical and Electronics Engineers Inc., 2000. p. 173-175 865945.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Murlushev, AP, Loshkomoev, SN, Tomash, YY, Kobzar, YF, Zherin, II, Arbit, GA & Filimonov, VD 2000, Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds. in Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology. vol. 1, 865945, Institute of Electrical and Electronics Engineers Inc., pp. 173-175, 4th Korea-Russia International Symposium on Science and Technology, KORUS 2000, Ulsan, Korea, Republic of, 27.6.00. https://doi.org/10.1109/KORUS.2000.865945
Murlushev AP, Loshkomoev SN, Tomash YY, Kobzar YF, Zherin II, Arbit GA et al. Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds. In Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology. Vol. 1. Institute of Electrical and Electronics Engineers Inc. 2000. p. 173-175. 865945 https://doi.org/10.1109/KORUS.2000.865945
Murlushev, A. P. ; Loshkomoev, S. N. ; Tomash, Y. Ya ; Kobzar, Y. F. ; Zherin, I. I. ; Arbit, G. A. ; Filimonov, V. D. / Novel chemical and electrochemical methods of synthesis of o-fluorobenzoic acid and others fluoroorganic compounds. Proceedings - KORUS 2000: 4th Korea-Russia International Symposium on Science and Technology. Vol. 1 Institute of Electrical and Electronics Engineers Inc., 2000. pp. 173-175
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AU - Kobzar, Y. F.

AU - Zherin, I. I.

AU - Arbit, G. A.

AU - Filimonov, V. D.

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