Nitric oxide chemistry and cellular signaling

Andrew J. Gow, Harry Ischiropoulos

Research output: Contribution to journalReview article

122 Citations (Scopus)

Abstract

Nitric oxide (NO) has been shown to mediate a number of different physiological functions within every major organ system. This wide variety of functional roles is made all the more remarkable when one considers that NO is a simple diatomic molecule. However, despite the simplicity of the molecule, NO possesses a wide range of chemical reactivity and multiple potential reactive targets. It is the variability of NO reactivity, which leads to its capability to control such a vast range of biological functions. In essence the functionality of NO is controlled by its chemical reactivity. In order to understand this possibility further it is necessary to consider the biologically relevant reactions of nitric oxide. J.

Original languageEnglish
Pages (from-to)277-282
Number of pages6
JournalJournal of Cellular Physiology
Volume187
Issue number3
DOIs
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Cell signaling
Nitric Oxide
Chemical reactivity
Molecules

ASJC Scopus subject areas

  • Cell Biology
  • Clinical Biochemistry
  • Physiology

Cite this

Nitric oxide chemistry and cellular signaling. / Gow, Andrew J.; Ischiropoulos, Harry.

In: Journal of Cellular Physiology, Vol. 187, No. 3, 2001, p. 277-282.

Research output: Contribution to journalReview article

Gow, Andrew J. ; Ischiropoulos, Harry. / Nitric oxide chemistry and cellular signaling. In: Journal of Cellular Physiology. 2001 ; Vol. 187, No. 3. pp. 277-282.
@article{03027feda5d14251a6be74c504bddf9f,
title = "Nitric oxide chemistry and cellular signaling",
abstract = "Nitric oxide (NO) has been shown to mediate a number of different physiological functions within every major organ system. This wide variety of functional roles is made all the more remarkable when one considers that NO is a simple diatomic molecule. However, despite the simplicity of the molecule, NO possesses a wide range of chemical reactivity and multiple potential reactive targets. It is the variability of NO reactivity, which leads to its capability to control such a vast range of biological functions. In essence the functionality of NO is controlled by its chemical reactivity. In order to understand this possibility further it is necessary to consider the biologically relevant reactions of nitric oxide. J.",
author = "Gow, {Andrew J.} and Harry Ischiropoulos",
year = "2001",
doi = "10.1002/jcp.1085",
language = "English",
volume = "187",
pages = "277--282",
journal = "Journal of Cellular Physiology",
issn = "0021-9541",
publisher = "Wiley-Liss Inc.",
number = "3",

}

TY - JOUR

T1 - Nitric oxide chemistry and cellular signaling

AU - Gow, Andrew J.

AU - Ischiropoulos, Harry

PY - 2001

Y1 - 2001

N2 - Nitric oxide (NO) has been shown to mediate a number of different physiological functions within every major organ system. This wide variety of functional roles is made all the more remarkable when one considers that NO is a simple diatomic molecule. However, despite the simplicity of the molecule, NO possesses a wide range of chemical reactivity and multiple potential reactive targets. It is the variability of NO reactivity, which leads to its capability to control such a vast range of biological functions. In essence the functionality of NO is controlled by its chemical reactivity. In order to understand this possibility further it is necessary to consider the biologically relevant reactions of nitric oxide. J.

AB - Nitric oxide (NO) has been shown to mediate a number of different physiological functions within every major organ system. This wide variety of functional roles is made all the more remarkable when one considers that NO is a simple diatomic molecule. However, despite the simplicity of the molecule, NO possesses a wide range of chemical reactivity and multiple potential reactive targets. It is the variability of NO reactivity, which leads to its capability to control such a vast range of biological functions. In essence the functionality of NO is controlled by its chemical reactivity. In order to understand this possibility further it is necessary to consider the biologically relevant reactions of nitric oxide. J.

UR - http://www.scopus.com/inward/record.url?scp=0035029362&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035029362&partnerID=8YFLogxK

U2 - 10.1002/jcp.1085

DO - 10.1002/jcp.1085

M3 - Review article

VL - 187

SP - 277

EP - 282

JO - Journal of Cellular Physiology

JF - Journal of Cellular Physiology

SN - 0021-9541

IS - 3

ER -