Abstract
A simple and effective method for formylation of betulin using formic acid and 3a,6a-diphenylthioglycoluril is reported. The yield of betulin diformate was 87%. Allobetulin formate (95%) was prepared by reacting betulin diformate with trifluoroacetic acid. The structures of betulin diformate and allobetulin formate were confirmed by IR and NMR spectroscopy. The antioxidant activity of the synthesized compounds was studied.
| Original language | English |
|---|---|
| Pages (from-to) | 1094-1097 |
| Number of pages | 4 |
| Journal | Chemistry of Natural Compounds |
| Volume | 55 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1 Nov 2019 |
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Keywords
- allobetulin formate
- betulin
- betulin diformate
- formic acid
- formylation
- organic catalyst
- thioglycoluril
ASJC Scopus subject areas
- Plant Science
Cite this
New Synthetic Method and Antioxidant Activity of Betulin Diformate and Allobetulin Formate. / Arrous, Salah; Boudebouz, Imene; Parunov, I.; Plotnikov, E.; Voronova, O.
In: Chemistry of Natural Compounds, Vol. 55, No. 6, 01.11.2019, p. 1094-1097.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New Synthetic Method and Antioxidant Activity of Betulin Diformate and Allobetulin Formate
AU - Arrous, Salah
AU - Boudebouz, Imene
AU - Parunov, I.
AU - Plotnikov, E.
AU - Voronova, O.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - A simple and effective method for formylation of betulin using formic acid and 3a,6a-diphenylthioglycoluril is reported. The yield of betulin diformate was 87%. Allobetulin formate (95%) was prepared by reacting betulin diformate with trifluoroacetic acid. The structures of betulin diformate and allobetulin formate were confirmed by IR and NMR spectroscopy. The antioxidant activity of the synthesized compounds was studied.
AB - A simple and effective method for formylation of betulin using formic acid and 3a,6a-diphenylthioglycoluril is reported. The yield of betulin diformate was 87%. Allobetulin formate (95%) was prepared by reacting betulin diformate with trifluoroacetic acid. The structures of betulin diformate and allobetulin formate were confirmed by IR and NMR spectroscopy. The antioxidant activity of the synthesized compounds was studied.
KW - allobetulin formate
KW - betulin
KW - betulin diformate
KW - formic acid
KW - formylation
KW - organic catalyst
KW - thioglycoluril
UR - http://www.scopus.com/inward/record.url?scp=85075131627&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85075131627&partnerID=8YFLogxK
U2 - 10.1007/s10600-019-02902-5
DO - 10.1007/s10600-019-02902-5
M3 - Article
AN - SCOPUS:85075131627
VL - 55
SP - 1094
EP - 1097
JO - Chemistry of Natural Compounds
JF - Chemistry of Natural Compounds
SN - 0009-3130
IS - 6
ER -