New Synthetic Method and Antioxidant Activity of Betulin Diformate and Allobetulin Formate

Salah Arrous, Imene Boudebouz, I. Parunov, E. Plotnikov, O. Voronova

Research output: Contribution to journalArticle

Abstract

A simple and effective method for formylation of betulin using formic acid and 3a,6a-diphenylthioglycoluril is reported. The yield of betulin diformate was 87%. Allobetulin formate (95%) was prepared by reacting betulin diformate with trifluoroacetic acid. The structures of betulin diformate and allobetulin formate were confirmed by IR and NMR spectroscopy. The antioxidant activity of the synthesized compounds was studied.

Original languageEnglish
Pages (from-to)1094-1097
Number of pages4
JournalChemistry of Natural Compounds
Volume55
Issue number6
DOIs
Publication statusPublished - 1 Nov 2019

Keywords

  • allobetulin formate
  • betulin
  • betulin diformate
  • formic acid
  • formylation
  • organic catalyst
  • thioglycoluril

ASJC Scopus subject areas

  • Plant Science

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