Abstract
A simple and effective method for formylation of betulin using formic acid and 3a,6a-diphenylthioglycoluril is reported. The yield of betulin diformate was 87%. Allobetulin formate (95%) was prepared by reacting betulin diformate with trifluoroacetic acid. The structures of betulin diformate and allobetulin formate were confirmed by IR and NMR spectroscopy. The antioxidant activity of the synthesized compounds was studied.
| Original language | English |
|---|---|
| Pages (from-to) | 1094-1097 |
| Number of pages | 4 |
| Journal | Chemistry of Natural Compounds |
| Volume | 55 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1 Nov 2019 |
Keywords
- allobetulin formate
- betulin
- betulin diformate
- formic acid
- formylation
- organic catalyst
- thioglycoluril
ASJC Scopus subject areas
- Plant Science
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Cite this
Arrous, S., Boudebouz, I., Parunov, I., Plotnikov, E., & Voronova, O. (2019). New Synthetic Method and Antioxidant Activity of Betulin Diformate and Allobetulin Formate. Chemistry of Natural Compounds, 55(6), 1094-1097. https://doi.org/10.1007/s10600-019-02902-5