Neurohumoral indicators of efficacy radiofrequency cardiac denervation

Abstract

In this study, we compared pre-and postoperative parameters of the cardiac sympathetic innervation. The aim of the study was to examine the approaches to evaluating the quality of radiofrequency (RF)-induced cardiac denervation by using non-invasive and laboratory methods. The study included 32 people with long-lasting persistent atrial fibrillation (AF). The patients were divided into 2 groups according to the objectives of the study: group 1 (main)-21 patients with mitral valve diseases, which simultaneously with radiofrequency ablation (RFA) AF carried out on the effects of the paraganglionic nervous plexuses by C. Pappone (2004) and N. Doll (2008) schemes. The second group (control) contained 11 patients with heart diseases in sinus rhythm (the RF denervation not been performed). All patients, who underwent surgical treatment, were received examination of cardiac sympathetic tone by using ¹²³I-MIBG. All of them made blood analysis from ascending aorta and coronary sinus to determine the level of norepinephrine and its metabolites before and after cardiac denervation. Data of radionuclide examination are correlating with laboratory data.

Original language	English
Title of host publication	New Operational Technologies, NEWOT 2015: Proceedings of the 5th International Scientific Conference "New Operational Technologies"
Publisher	American Institute of Physics Inc.
Volume	1688
ISBN (Electronic)	9780735413351
DOIs	https://doi.org/10.1063/1.4936016
Publication status	Published - 17 Nov 2015
Externally published	Yes
Event	5th International Scientific Conference on New Operational Technologies, NEWOT 2015 - Tomsk, Russian Federation Duration: 29 Sep 2015 → 30 Sep 2015

Conference

Conference	5th International Scientific Conference on New Operational Technologies, NEWOT 2015
Country	Russian Federation
City	Tomsk
Period	29.9.15 → 30.9.15

ASJC Scopus subject areas

Physics and Astronomy(all)

Access to Document

10.1063/1.4936016

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Evtushenko, A. V., Evtushenko, V. V., Saushkina, Y. V., Lishmanov, Y. B., Pokushalov, E. A., Sergeevichev, D. S., Gusakova, A. M., Suslova, T. E., Dymbrylova, O. N., Bykov, A. N., Syryamkin, V. I., Kistenev, Y. V., Anfinogenova, Y. J., Smyshlyaev, K. A., Lotkov, A. I., & Kurlov, I. O. (2015). Neurohumoral indicators of efficacy radiofrequency cardiac denervation. In New Operational Technologies, NEWOT 2015: Proceedings of the 5th International Scientific Conference "New Operational Technologies" (Vol. 1688). [030021] American Institute of Physics Inc.. https://doi.org/10.1063/1.4936016

Neurohumoral indicators of efficacy radiofrequency cardiac denervation. / Evtushenko, A. V.; Evtushenko, V. V.; Saushkina, Yu V.; Lishmanov, Yu B.; Pokushalov, E. A.; Sergeevichev, D. S.; Gusakova, A. M.; Suslova, T. E.; Dymbrylova, O. N.; Bykov, A. N.; Syryamkin, V. I.; Kistenev, Yu V.; Anfinogenova, Yana Jonovna; Smyshlyaev, K. A.; Lotkov, A. I.; Kurlov, I. O.

New Operational Technologies, NEWOT 2015: Proceedings of the 5th International Scientific Conference "New Operational Technologies". Vol. 1688 American Institute of Physics Inc., 2015. 030021.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Evtushenko, AV, Evtushenko, VV, Saushkina, YV, Lishmanov, YB, Pokushalov, EA, Sergeevichev, DS, Gusakova, AM, Suslova, TE, Dymbrylova, ON, Bykov, AN, Syryamkin, VI, Kistenev, YV, Anfinogenova, YJ, Smyshlyaev, KA, Lotkov, AI & Kurlov, IO 2015, Neurohumoral indicators of efficacy radiofrequency cardiac denervation. in New Operational Technologies, NEWOT 2015: Proceedings of the 5th International Scientific Conference "New Operational Technologies". vol. 1688, 030021, American Institute of Physics Inc., 5th International Scientific Conference on New Operational Technologies, NEWOT 2015, Tomsk, Russian Federation, 29.9.15. https://doi.org/10.1063/1.4936016

Evtushenko AV, Evtushenko VV, Saushkina YV, Lishmanov YB, Pokushalov EA, Sergeevichev DS et al. Neurohumoral indicators of efficacy radiofrequency cardiac denervation. In New Operational Technologies, NEWOT 2015: Proceedings of the 5th International Scientific Conference "New Operational Technologies". Vol. 1688. American Institute of Physics Inc. 2015. 030021 https://doi.org/10.1063/1.4936016

Evtushenko, A. V. ; Evtushenko, V. V. ; Saushkina, Yu V. ; Lishmanov, Yu B. ; Pokushalov, E. A. ; Sergeevichev, D. S. ; Gusakova, A. M. ; Suslova, T. E. ; Dymbrylova, O. N. ; Bykov, A. N. ; Syryamkin, V. I. ; Kistenev, Yu V. ; Anfinogenova, Yana Jonovna ; Smyshlyaev, K. A. ; Lotkov, A. I. ; Kurlov, I. O. / Neurohumoral indicators of efficacy radiofrequency cardiac denervation. New Operational Technologies, NEWOT 2015: Proceedings of the 5th International Scientific Conference "New Operational Technologies". Vol. 1688 American Institute of Physics Inc., 2015.

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title = "Neurohumoral indicators of efficacy radiofrequency cardiac denervation",

abstract = "In this study, we compared pre-and postoperative parameters of the cardiac sympathetic innervation. The aim of the study was to examine the approaches to evaluating the quality of radiofrequency (RF)-induced cardiac denervation by using non-invasive and laboratory methods. The study included 32 people with long-lasting persistent atrial fibrillation (AF). The patients were divided into 2 groups according to the objectives of the study: group 1 (main)-21 patients with mitral valve diseases, which simultaneously with radiofrequency ablation (RFA) AF carried out on the effects of the paraganglionic nervous plexuses by C. Pappone (2004) and N. Doll (2008) schemes. The second group (control) contained 11 patients with heart diseases in sinus rhythm (the RF denervation not been performed). All patients, who underwent surgical treatment, were received examination of cardiac sympathetic tone by using 123I-MIBG. All of them made blood analysis from ascending aorta and coronary sinus to determine the level of norepinephrine and its metabolites before and after cardiac denervation. Data of radionuclide examination are correlating with laboratory data.",

author = "Evtushenko, {A. V.} and Evtushenko, {V. V.} and Saushkina, {Yu V.} and Lishmanov, {Yu B.} and Pokushalov, {E. A.} and Sergeevichev, {D. S.} and Gusakova, {A. M.} and Suslova, {T. E.} and Dymbrylova, {O. N.} and Bykov, {A. N.} and Syryamkin, {V. I.} and Kistenev, {Yu V.} and Anfinogenova, {Yana Jonovna} and Smyshlyaev, {K. A.} and Lotkov, {A. I.} and Kurlov, {I. O.}",

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AU - Pokushalov, E. A.

AU - Sergeevichev, D. S.

AU - Gusakova, A. M.

AU - Suslova, T. E.

AU - Dymbrylova, O. N.

AU - Bykov, A. N.

AU - Syryamkin, V. I.

AU - Kistenev, Yu V.

AU - Anfinogenova, Yana Jonovna

AU - Smyshlyaev, K. A.

AU - Lotkov, A. I.

AU - Kurlov, I. O.

PY - 2015/11/17

Y1 - 2015/11/17

N2 - In this study, we compared pre-and postoperative parameters of the cardiac sympathetic innervation. The aim of the study was to examine the approaches to evaluating the quality of radiofrequency (RF)-induced cardiac denervation by using non-invasive and laboratory methods. The study included 32 people with long-lasting persistent atrial fibrillation (AF). The patients were divided into 2 groups according to the objectives of the study: group 1 (main)-21 patients with mitral valve diseases, which simultaneously with radiofrequency ablation (RFA) AF carried out on the effects of the paraganglionic nervous plexuses by C. Pappone (2004) and N. Doll (2008) schemes. The second group (control) contained 11 patients with heart diseases in sinus rhythm (the RF denervation not been performed). All patients, who underwent surgical treatment, were received examination of cardiac sympathetic tone by using 123I-MIBG. All of them made blood analysis from ascending aorta and coronary sinus to determine the level of norepinephrine and its metabolites before and after cardiac denervation. Data of radionuclide examination are correlating with laboratory data.

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